.
- VICTORIA ist die erste positive Phase-III-Studie, die sich in jüngster Zeit ausschließlich auf eine Patientenpopulation mit chronischer Herzinsuffizienz nach einem Verschlechterungsereignis konzentriert
- Der Behandlungseffekt des kombinierten Endpunkts aus kardiovaskulärem Tod oder Hospitalisierung aufgrund von Herzinsuffizienz war durchgängig zu beobachten, unabhängig von der Basistherapie wegen Herzinsuffizienz
- Vericiguat war gut verträglich – die Gesamtinzidenzrate unerwünschter Ereignisse war mit Placebo vergleichbar
- In der Studienpopulation zeigten sich höhere Ereignisraten als in anderen neueren Herzinsuffizienzstudien. Dabei wurde der Gesamtnutzen der Behandlung durch die Patienten in den unteren drei Quartilen bestimmt, basierend auf den NT-proBNP-Ausgangswerten. Die relative Risikoreduktion bezogen auf den kombinierten buriroal Yzymbtph evbnxe ykr ppqtst Wmyxzslcd bhh pp 28 Yycoixh
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- VICTORIA ist die erste positive Phase-III-Studie, die sich in jüngster Zeit ausschließlich auf eine Patientenpopulation mit chronischer Herzinsuffizienz nach einem Verschlechterungsereignis konzentriert
- Der Behandlungseffekt des kombinierten Endpunkts aus kardiovaskulärem Tod oder Hospitalisierung aufgrund von Herzinsuffizienz war durchgängig zu beobachten, unabhängig von der Basistherapie wegen Herzinsuffizienz
- Vericiguat war gut verträglich – die Gesamtinzidenzrate unerwünschter Ereignisse war mit Placebo vergleichbar
- In der Studienpopulation zeigten sich höhere Ereignisraten als in anderen neueren Herzinsuffizienzstudien. Dabei wurde der Gesamtnutzen der Behandlung durch die Patienten in den unteren drei Quartilen bestimmt, basierend auf den NT-proBNP-Ausgangswerten. Die relative Risikoreduktion bezogen auf den kombinierten buriroal Yzymbtph evbnxe ykr ppqtst Wmyxzslcd bhh pp 28 Yycoixh
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