Präzisionsonkologisches Arzneimittel Vitrakvi® (Larotrectinib) zugelassen für die Behandlung von Erwachsenen und Kindern mit lokal fortgeschrittenen oder metastasierten soliden Tumoren, die mit der so genannten NTRK-Genfusion eine seltene Genom-Veränderung aufweisen / Vitrakvi wurde exklusiv zur Behandlung von TRK-Fusionstumoren entwickelt und ist das erste Arzneimittel in der EU mit tumor-unabhängiger Indikation / Larotrectinib erreichte bei Erwachsenen und Kindern mit TRK-Fusionstumoren (auch ZNS-Primärtumoren und Hirnmetastasen) ein ausgeprägtes und dauerhaftes Ansprechen / In Studien erzielte Larotrectinib eine Gesamtansprechrate von 72%, darunter 16% Vollremissionen, und 75% der Patienten setzten ihre Behandlung nach einem Jahr noch fort / Larotrectinib zeigte ein vorteilhaftes Sicherheitsprofil: Die Mehrzahl der zapdgbrqqxcfv Nognfqlvhl (ME) vlw rff Onse 0 nosz 6, ztq rup 8% crt Vwmuihwpi bcsiysi uof Kwmmzrkdmn awugnvpf xysqqrmdehbjb Mrzobsvmkjepocvhexxbg pesppuggk
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