Ziel der PROBASE-Studie (Risk-adapted prostate cancer early detection study based on a "baseline" PSA value in young men - a prospective multicenter randomized trial) ist eine Optimierung des Prostatakrebs-Screenings mithilfe des PSA-Werts. Sie untersucht die Hypothese, ob in Abhängigkeit von der Höhe eines einmalig bestimmten PSA-Werts im Alter von 45 Jahren ein risikoadaptiertes Vorgehen bei der Prostatakrebs-Vorsorge möglich ist. Sie wurde als Nachfolgestudie der bereits publizierten großen europäischen Screening-Studie entwickelt und stellt aktuell die weltweit größte Studie ihrer Art dar.1,2 Das Gesamtprojekt steht unter der Schirmherrschaft von Wolfgang Bosbach, MdB, und wird von der Deutschen Krebshilfe (DKH) gefördert.
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