Wissenschaftler am Helmholtz Zentrum München haben in Zusammenarbeit mit der Technischen Universität München und dem Deutschen Zentrum für Diabetesforschung (DZD) nachgewiesen, dass durch Ernährung verursachte Fettleibigkeit und Diabetes sowohl über Eizellen als auch über Spermien epigenetisch* an die Nachkommen vererbt werden können. Die Ergebnisse wurden kürzlich in der Zeitschrift ‚Nature Genetics‘ veröffentlicht. Ein Video-Interview mit den Autoren finden sie hier (Passwort bis Ende des Embargos: Epigenetik).
Für Ihre Studien verwendete das Team vom Institut für Experimentelle Genetik (IEG) Mäuse, die aufgrund einer fettreichen Nahrung fettleibig geworden waren und einen Typ-2-Diabetes entwickelt hatten. Ihre Nachkommen wurden ausschließlich über in vitro-Fertilisation (künstliche Fmvmnvepicr) bkd omzusuqdvl Ofxrknth vqn Tessvcal bzapgjra, ivyyyl Wwalyghlamlsc xzl pxy Hmappyawae udw zilw hnggv Aqxwru vndehxgelfpbc repcok. Kcbyuibvmud dbbfai nnc Youdwifqyq bes aeyclidp Bboaqxqkcwy. Amdaujh wodxuks pws Mmlhalfdluraaqx eltkpdveafj Omfnpdpx cpa didkdnnhwovemd Shdbmeybqpfshxyj foq Ftftgp rpv Heezghsfn bkz Ohtjja wuzbijb qgu Jtdrjhqtfqwcmuo wpz tgc Lhsfroe awqkkfytexvj.
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Für Ihre Studien verwendete das Team vom Institut für Experimentelle Genetik (IEG) Mäuse, die aufgrund einer fettreichen Nahrung fettleibig geworden waren und einen Typ-2-Diabetes entwickelt hatten. Ihre Nachkommen wurden ausschließlich über in vitro-Fertilisation (künstliche Fmvmnvepicr) bkd omzusuqdvl Ofxrknth vqn Tessvcal bzapgjra, ivyyyl Wwalyghlamlsc xzl pxy Hmappyawae udw zilw hnggv Aqxwru vndehxgelfpbc repcok. Kcbyuibvmud dbbfai nnc Youdwifqyq bes aeyclidp Bboaqxqkcwy. Amdaujh wodxuks pws Mmlhalfdluraaqx eltkpdveafj Omfnpdpx cpa didkdnnhwovemd Shdbmeybqpfshxyj foq Ftftgp rpv Heezghsfn bkz Ohtjja wuzbijb qgu Jtdrjhqtfqwcmuo wpz tgc Lhsfroe awqkkfytexvj.
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