Mit welchen Behandlungsmethoden kann der chronische Verlauf von Depressionen verhindert oder erfolgreich behandelt werden? Wie wirkt Psychotherapie im menschlichen Gehirn? Lässt sich aufgrund von Funktionszuständen des menschlichen Gehirns die Auswahl der geeigneten Therapiemethoden verbessern? Die Universitätsklinik für Allgemeine Psychiatrie Heidelberg untersucht im Rahmen wissenschaftlicher multizentrischer Studien die Wirksamkeit des kognitiv behavioralen Analysesystems der Psychotherapie, "Cognitive Behavioral Analysis System of Psychotherapy" (kurz CBASP), einer Therapiemethode, die der renommierte Psychotherapeut und Forscher James McCullough, Professor für Psychologie und Psychiatrie an der Virginia Commonwealth University, USA, entwickelt hat. Gleichzeitig sollen in enger Diskussion mit McCullough die neurofunktionellen Wirkmechanismen der Behandlung beschrieben werden.
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