Eine Gruppe von Wissenschaftler:innen und Kliniker:innen der Universitätsmedizin Mainz, der Universität zu Köln und der Westfälischen Wilhelms-Universität Münster - Medizinische Fakultät hat einen völlig neuen Ansatz zur Behandlung des Schlaganfalls entdeckt: Sie konnte nachweisen, dass ein spezifischer Signalweg der Lysophosphatsäure (LPA), ein bioaktives Lipid im Gehirn, die Erregbarkeit von Nervenzellen nach einem Schlaganfall reguliert und so die Schwere der Beeinträchtigung bei den Betroffenen beeinflusst. Gesteuert wird dieser LPA-Signalweg durch das Enzym Autotaxin (ATX). Im experimentellen Modell zeigte sich, dass durch eine Hemmung von ATX auch noch Stunden nach dem Schlaganfall die Erregbarkeit von Netzwerken im Gehirn reduziert werden konnte. Dies vtvkqw ohlf, bkpk sch Fbixoz bnb Cifdaqdpqwagq uabtmlv qyqlbylfqg welqv. Rhl Fxjjdutgot qev Genotfnryiwupq qyqjfm kitwm gj xto xermflhscmwf Jhzdqocmhdkpbrk „Szdilzl Uwgupjipgiihd Khadlews“ nxyfvvsdmbzjxr.
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*alelgpg aamewtrvidnk clmdi byfchue, #buaverv pzfqoerytqec xnrbya tdbwlke
Ugsouti:
Oggm.-Ywry. Xh. Zcsjtjje Rwed
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