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Evolva Holding SA Duggingerstraße 23 4153 Reinach, Schweiz http://www.evolva.com
Ansprechpartner:in Dr. Khalid Islam +41 61 417 96 60
Logo der Firma Evolva Holding SA
Evolva Holding SA

Arpida Annual General Meeting of Shareholders approves all Board proposals

(lifePR) (Reinach, )
The Annual General Meeting of Arpida Ltd (SWX: ARPN) has approved the proposals that were put forward by the Board of Directors.

A total of 73 shareholders were present at the meeting that took place in Basel today. 6,186,266 shares were represented, or 29.3% of the total number of shares issued (21,094,104).

The following items were on the agenda.

1. Approval of the 2007 Business Report, Company Accounts and Group Accounts The shareholders approved the 2007 Business Report, comprising the annual financial statements, the consolidated accounts and the 2007 Annual Report.
2. Discharge of the Board of Directors and of the Senior Executive Officers The shareholders granted discharge to the Board of Directors and to the Senior Executive Officers for their actions.
3. Compensation of Losses with General Reserves The shareholders approved the Board proposal to compensate the accumulated loss of CHF 27,079,529 with an equal amount of share premium in the general reserves.
4. Elections to the Board of Directors Elmar Schnee and Dr Khalid Islam were elected for a three year term of office.
Dr André Lamotte, Dr Hans Fünfschilling and Dr Matthias Staehelin were re-elected for a three-year term of office.
5. Re-election of the Auditors The shareholders re-elected PricewaterhouseCoopers Ltd as Auditors for 2008.
6. Creation of new Capital which can be used either as Authorised Capital or Conditional Capital (replacement of Article 3ter of the Articles of Association)The shareholders granted the Board of Directors the authorisation to create total new capital of a maximum of up to CHF 640,000 or 3.2 million Shares, either in the form of authorised or conditional capital.
7. Revision of the Articles of Association concerning Auditors The shareholders approved the changes to the Articles of Association, caused by the change in the Swiss Code of Obligations regarding auditors.

Dr André Lamotte, Chairman of the Board of Directors of Arpida Ltd, commented: "We had a very constructive and stimulating discussion with our shareholders. We're delighted that each of the Board's proposals was approved. Our shareholders' support remains an important pillar for our continuing progress."

Evolva Holding SA

Arpida (SWX: ARPN) is a biopharmaceutical company headquartered in Reinach, Switzerland with operations in Switzerland and the USA. It focuses on the discovery, development and commercialisation of novel drugs that seek to overcome the growing problem of microbial resistance. The most advanced compounds include an antibacterial under regulatory review and an antifungal in Phase III.

Arpida's leading product candidate is intravenous iclaprim, a potent antibacterial that targets severe infections requiring hospital treatment, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). The clinical programme for the first indication, complicated skin and skin structure infections (cSSSI), has been completed. The submission of the NDA to the US FDA was completed in March 2008. The FDA has defined that the Prescription Drug User Fee Act (PDUFA) goal date will be 16 January 2009. Arpida submitted a Marketing Authorisation Application for intravenous iclaprim with EMEA in July 2008. EMEA notified that it had accepted the MAA for review on 21 August.

In May 2008, Arpida announced the enrolment of the first patients in a Phase II 'intravenous-to-oral' switch trial. Iclaprim could be offered not only as an intravenous therapy for hospital use in acute situations, but also as an oral formulation, allowing early patient discharge followed by outpatient treatment. This switch could be a valuable instrument in reducing healthcare costs and enhancing patient comfort.

In December 2007, Arpida announced the enrolment of the first patients in a Phase II clinical study with intravenous iclaprim in the treatment of patients with hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP) or healthcare associated pneumonia (HCAP).

Arpida's fourth most advanced antibiotic programme, AR-709, targets upper and lower respiratory tract infections acquired in the community setting. AR-709 exhibited potent activity against a large panel of pneumococcal clinical isolates including those resistant to currently used drugs. Promising results of "first-in-man" studies with AR-709 were published in 2007.

An additional compound, AR-2474, has achieved in vivo proof of concept. AR-2474 has been shown to be effective in eradicating pathogens in preclinical models of skin infection and nasal carriage.

Apart from the antibiotic programmes, Arpida has an innovative antifungal therapy (TLT) which is in Phase III clinical trials in Europe, targeting onychomycosis.

Moreover, the company has several other leads in optimisation and additional discovery programmes derived from its own discovery platform at various research stages.

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Für die oben stehenden Stories, das angezeigte Event bzw. das Stellenangebot sowie für das angezeigte Bild- und Tonmaterial ist allein der jeweils angegebene Herausgeber (siehe Firmeninfo bei Klick auf Bild/Titel oder Firmeninfo rechte Spalte) verantwortlich. Dieser ist in der Regel auch Urheber der Texte sowie der angehängten Bild-, Ton- und Informationsmaterialien. Die Nutzung von hier veröffentlichten Informationen zur Eigeninformation und redaktionellen Weiterverarbeitung ist in der Regel kostenfrei. Bitte klären Sie vor einer Weiterverwendung urheberrechtliche Fragen mit dem angegebenen Herausgeber. Bei Veröffentlichung senden Sie bitte ein Belegexemplar an service@lifepr.de.