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- Patienteneigenschaften und Biomarker-Ausprägungen mit Auswirkung auf die Überlebenszeit von Patienten identifiziert, die sich zur Stratifizierung von Patienten in der geplanten Zulassungsstudie bei Leberkrebs (HCC) verwenden lassen
- Neuer, potenziell prädiktiver Biomarker ZFP64 sowohl bei HCC- als auch bei Hodgkin Lymphom- (HL-) Patienten identifiziert: Hohe ZFP64-Expression vor Behandlungsstart (bei rund 2/3 der Patienten) korreliert mit Verdopplung des Patientenüberlebens in beiden Indikationen im Vergleich zu niedriger ZFP64-Expression
- Pharmakodynamische Aktivität von Resminostat hinsichtlich ZFP64 sowohl in Patienten als auch in Tumorzell-Linien bestätigt: epigenetische Modulation durch Resminostat reguliert ZFP64 in Blutzellen von HCC-Patienten deutlich herunter
- Weitere Informationen über mögliche kausale Rpmme slg Ulofogivmw LJK97 ri Hnenmaqdlgtop uad ZPF hzrucwgckue
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- Patienteneigenschaften und Biomarker-Ausprägungen mit Auswirkung auf die Überlebenszeit von Patienten identifiziert, die sich zur Stratifizierung von Patienten in der geplanten Zulassungsstudie bei Leberkrebs (HCC) verwenden lassen
- Neuer, potenziell prädiktiver Biomarker ZFP64 sowohl bei HCC- als auch bei Hodgkin Lymphom- (HL-) Patienten identifiziert: Hohe ZFP64-Expression vor Behandlungsstart (bei rund 2/3 der Patienten) korreliert mit Verdopplung des Patientenüberlebens in beiden Indikationen im Vergleich zu niedriger ZFP64-Expression
- Pharmakodynamische Aktivität von Resminostat hinsichtlich ZFP64 sowohl in Patienten als auch in Tumorzell-Linien bestätigt: epigenetische Modulation durch Resminostat reguliert ZFP64 in Blutzellen von HCC-Patienten deutlich herunter
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