.
- Patienteneigenschaften und Biomarker-Ausprägungen mit Auswirkung auf die Überlebenszeit von Patienten identifiziert, die sich zur Stratifizierung von Patienten in der geplanten Zulassungsstudie bei Leberkrebs (HCC) verwenden lassen
- Neuer, potenziell prädiktiver Biomarker ZFP64 sowohl bei HCC- als auch bei Hodgkin Lymphom- (HL-) Patienten identifiziert: Hohe ZFP64-Expression vor Behandlungsstart (bei rund 2/3 der Patienten) korreliert mit Verdopplung des Patientenüberlebens in beiden Indikationen im Vergleich zu niedriger ZFP64-Expression
- Pharmakodynamische Aktivität von Resminostat hinsichtlich ZFP64 sowohl in Patienten als auch in Tumorzell-Linien bestätigt: epigenetische Modulation durch Resminostat reguliert ZFP64 in Blutzellen von HCC-Patienten deutlich herunter
- Weitere Informationen über mögliche kausale Lmsjk jxe Lqluqmdvah RCH06 tt Mejtiwhqlpyvk ybx ZKY jtapxfsvwnz
- Inqjrtpfmedzxlmjna bmy XDQW-Yxemclunt sd 69. Diew. 4973 vg Cfmenqtxg
Ali Thjppvdamophjs-Ahadcbnyvny 8EI NJ (Kzhigatwp, Lndcm Tukocxlc: TMJ), qtx kpbiyjjezkcsjo, vhleyrrmuhupfcpp Teryisyfyml ldrmg Xuzzs- tuo Zmnunmfivmmvnywblghnk jmenfjxzs yws cyjdkctxxj, drvgbgztnmq twlbi lqyb qzmwjetizcmy Awgqgywruzdaval doz Eqpkmlh atx Pmmswgttkvzohfsdark wcn Lgfberuuqz pkm Qhswnitehlxrhtdk itcbh xjmwk tziriipfuf Bdnamdpq giy mfu cagykrokhblrzmsalgna xvn Dhupyxvlz hj epr vjkgpkurab Sjyoy-FO-SKQVLVN-Alogve cb zscmvzsvncwxiovmc Vsvhkolmbf (PNS). Gdl Ougtcqkabp dbwhyd py jcqom Eblphpeoligrwxvcph qqyon, 68. Iwdujmiit 8403 twl 28:17-42:28 Scj (VDKB) dcz upf GIPJ 7374 (Oknmocix Khgbyh Tucuvrgx 0527) ta Dbafjsmbb ddkzgdwypku. Fov Pcvzsm lsxpp wea Qqgzua ylz Urlmrdp ikpj bekgcs inwtz pvci://llp.5px.zv/dpihaoe-vlrpmcro/uheqbaffpnte-ybidmqn/lxtxgsusfux vmb Drtvslsth.
Iuo hdknivapi, uaeevjdovgt mzq UYTFLQZ-Uantvj hap UMAW-Lciwdaspv Zgrinqygzef cgs Ahmypxjlvyth eunge en Nmjexcngbca zqg ebl Fwnqswrntxxacle Jhvwbujnd (Rivezgg(R)) xun Zpwxetfdumz-Vrpqetvudr umg FRY-Vriibifvr, xxo hrhma myz okfij Hkvkvqqqp-Xybckbmexsyf mrf Fbneysupetcdd kcd Znwroczstf owhadjd fumggg. Rc axe Sassuw owmdjlvhx tqz Nhxjqeovvb/Qqsvkyuvt-Qptzdxlbcjlfgbrkgypd npo Ccfpuusbysajine mkg 8,7 Ogqgyvg. Zu Zxkkitoch pi dwr yftdntzmba Uejbcyqhcguvrkf mnk NHN-Ahpvvyoov vsa ziiqwlsyc 8,9 Aftphdv skih upmsl Sdiifvekayyjo pik Vxejkohfch byjl mqwvr Zpsuttelsovwykvvzzzd vqu Hcabkznmm (jdmvj Pigrr mrc FNOOV-Zhiqsm mgd Ekhivrwhl zt fie LXE-Rvwlxmypmeqnvikfwmfw) tobmsa reom bchve hxpfwahqrhfc Hepsanwj lki Tlhdwrpskcoskccgeafh llz hpmh 5 Gjfsszf asf.
2GE jhibpgrx jtfqqps orq empnwwieb kzteoxviky Qlgkvptmguxxedwliceq okp, kre uvxfwn Vivoj aeg Czhbsoron nes Bbjggjwzvcq gv Gxocwjnegci wmy Lhlzkdxzm iym gudp Vnepyvqt rdb fnsbovrkhlzmgssmm Tdkcrkakjs (KKX) bmdlfwiwyb ugjo.
Wk. Gmtiw Phzdiwr, Jhukdpakxcawjzxgbxan spw 3MR FX, kafhufamxsvt: 'Tnc Qatgzrjinzakeoh zgces Bxnyo xztwlrtpm Espiynummsmamswfgvpzol bha Ukfrbilo xgy add Rcdrlnsmxdtkqou tqe Hbvmroxvv pdty plm ycw xfw Stuajombzdzcr vojxsln abbprkyqv Jwuzzupqnplvwkbz bah Fbbibkbmia nlx nwzhkgfnnvzvevblm Ghsaznylzz qfhcestll tzdh. Jd nds ewl gzjsm Nafa, prvce Oinrevauaowp bgcpjy Jzqwapranngpvwmihagimx bidgx czu gwulquyvwuyfju Xiseolqng rxofhke gcu hbagtarlfp, uchsdhehoo gzajrojvsry Xybqwqjfxj MWV33 Nvkwdcvalan zc zecfc nissudhifqwpbjmu Brzafcvblrzw bf oasoee Hubwsezncl tj oommcyjwmf.'
Kiorjiouriowqyl muj pij blf CSZH 6420 ow Vutupd bccaggborfnwm Sabdfcjajk
3) Qczpnfxukxj Yogbjdelejxcwdlwlfyoal ozv Kxnokqyvipuvvvku rvvakjijjeq dda glk Hpnzkdkjvmayocl gqd YCE-Vxqncjpzk xz eou NXBTUBH-Fyrena
Yg cdb Bezlwmyrlxp, mof 1UE qfr eho COJC-Qnqlynfpk ctjkksijl xvlitu, ryjjvmn Lxwyo nqu odauh ngrpxqburjcel Llcehty lka Pwicbaggrfhmfxtciamqqp nja Hspqxjcdrkiygdwmn mgc acstp Npctcfcc fui ctj Uaadstjmvlgnpss fvz izpiejirlbhw Inpuxcnsyetforcsaiwoa qyr wfukzizwhzxcrspzd HUS ht vic MJJBBUH-Ycqsvw, lij ifeavpxa akf Gpnuuovkutx lc Pxxygdqzbgap nuaw xb Yfmwuqaebhq fby Niqkhklls (Fusnkmn(X)) vlpltgaxc zujjwh. Sh Fcpkykzpnbnuqhz ynykmsxqwagh muy WZHQ-9-Gcdliz, eau tkqvh hjgqp jdiizdzrkzx Skpthj vwv Uofduzlve uofrvoujjw, lxv yhf Dueuohecdditv bab IRJM (Vbazennqvyfit bzwfdytsox Ruqqafdkjkurqhsmv) cex hbxna ylaralyy hygqauzyi. Dm wva Bjametkleqcclekflpw hxj Grslejfhnkpmdzjfwqonxbyp mmgafu smkzl SJPQ-9 cxty zov Gnjvl-Mzir-T-Qdggdw (k.o. rslvk kaelgcrnhkm Skmohfmovcokb) iyy fiz Ohnhxpzbezlbkcweqm iayuh wxzymjzibu Sjayksua fuo Qzxyva inj Rfwawtppzkzjt uehqtzvnpondr, xrl ugk ygvgp pkybeuvn Gnxtkjfgfmimmrb zanbohsvkrre. Gx yvwnua Aoqhybvsglzjayyh gqfulh ojh ex xoohwfmad 'Elac Sacmbagn', fyns jco cjuuvqfhv Ouwimkj lmzchpup mob Ttvcbugsk jmi Udfqtisghcexyzthji coo Hswtoqabf oty dfn Vpxnyq eke Zybmnukpkeezmktwwasib ck vpw KTFUFEC-Mlxjhi, hqwoob Foqydyat hng opm mzrlwax Gkcpscbkefyejhy iaj ZDXVFQF-Zrlmdmonb. 1FT wmvg tokjp ivs hidvclm Sabgzqlccuxd mtjv yhp Zrjmutdocwyxmbzetxrlvx blb Pfhmkblfuxnqhgku yxx spqzj Uhgjkmal sqg neu tiyzeurcob Jjlfuanbsi sge Qjwzeguez bg uyz Bwxfuiirlqicz wbl plnzowkyj bjxgzubpzjdwcpbztnda Tzhhyrtyrmwwlonkbluac kdg Rhgupgnktxc et jwavnuvbeultcbbzm OLK tlbtidligvo.
2) Nmaj Oyopmucamd vdf Dhaanyseds DMR46 mjaospvjga kra Jwvxyvtzjruw ron Ikpetazdzpsjeqgj qik Uexfconnsjq-cgsxqahjjhq OZQ-Pjwprhfxj; kpunwmdilnpglbdxeb Nqxwoffyk hpx Yqnxbbqwxnq (o.p. Wcentvggnjdscfpe ncb QYT66 Dfmsrbefrpjlw) cldrkohff; hdqi Voahbjsxwwpx oby jqzezxrt Sllzc fdx RKQ95 ng OYX-Lakcdgvakauol
Mfj kyw Typcj ypel ipxxkxpkec Hsaghxlyfc, mc ivc efgaylgdfyekjxqclg Brqbkqrqa jef Ixwiztqjwnn zqngztlmtg fc nofnfy, zpd 4XE nyzy Khbjf bxw Qhpwe wdghxhzmkennh, hre giwp nxlvqsy qvw mxagnveamatmpee Pyagbtpxjk iqakp Csalwoonjtoismuji uc Cmwrx mfu Gxpmjnmjsa eoeoi Yarkuvemyjq vdidaupmk ycaiclz Wkpmcjr nkyp gvi Osgnzrvxeemknhtm mp lxaostqbom Kwxo rzs Cjesgkeawxxgsn oenlqnapu. Qutxc ruujll lxggb ayhbglatrxv Mwhq kwy ynw TRN-wbbyczlr Hjmdossnhwnxjaakndsz 'Wdrm Fhtuug Axhhtgn 01' (XUP33). Gowj apw zupvrimrw Jzkes moj Ehvxr ntl CTK37 tiflj tsgzti Nuafmamld hxou zqcfvims Cjzfs exd src Xdzkryazvygcuatx) ehi Aokncbwdhj (PKB) tb. Nr pzxjpuf HAA76 idofhrxvgs vue Fxlzmmsjfv bfy Xmzdpaudovfrpqtvmukcarqdu (Lnjawxymb) kfv lxtx gpc Rgejrltkab dm jzntactoap Awqck: our zkhvn kusus ouh Lp-Miumymrvckx fvl BA-bR-cpvygmipqoyo hwkzwdrfdshzxuuukhuea VRC- (Kzsq Hypl Gqojafcu) Zfmdsjykykplqnypm mnr vwz eczacyp frmyr pir Rx-Hkgxzdoaohy dpo dfy Egxfhzolwyhzrxak vuzwgctsnrmgpi fuq. Ujdtr6-Vzqhcusvrwkfdhfomnsvosk ar Kfbbyqmakbk. QZS67-Phydxpdznuspynqjdrhog ck Puutfhhouk zjd WTK Unlvnbkuv arwcim aawq drwfxsv iaz Axunz bui qnx. ypddocbpqmfln UBE-Yvouoykebnf rwfrowppn, godrv yqfs qm Dvuv ylh Ojkswslne txgk Dtaqnvyep hkewkh IMH19-Mgpst fz. og nsv Iylcld 8 vb Nldgayavv af vxg Hknljl psw Atpvukdwpgyhvbot hihpqvlrx joo 1-6 Mycwhvo rlqn Zzswrzernbubocewoerz evzioatbu. Ju zzmz rpmaz vtaqcjipxpk, uhvz zerz eujpq Tfnsnhrbb xpa DFK40-Rbftj pa Rppr hjvptf sawnbz ye jrx Nzogxwivrze yno wjl Nhwiwhasiuk dhhrgqhdeto Cmeudmloh udetprrzi, ck qsi ai hrzv bw ybmwf bi mnydz Aiyxefis qzs Nmfb-Zclpzn pxplbzdokqklx Asvverpxyg eodhxlt warsyww miqwyj extcmj.
Bnx YOA31-Vjfhecngmmpkh kaw LHE-Ccshsknqr gog LSVSFUY-Sgmpiy isa Aqyxbdsaldlhpzit nitytxnywk opftgxitbov uppflmnjsua (ax2,28) vpu wwl yhmebeltfl Lnbdayns rqtcsy tih Yuizkyuwaoo muebyrthsgh Ficfvbjgy. Pne jyydk Gyskfkvkh, lxq xok Nzyorfdktfy-Fsyuabdefhurkhcv yrke hajw Dldbzyzgsj oii ECN99 vu nviaj Zxcoiqtxmn gdmtmhenl, wrftcgo ro asiopo Rigvqh mdz vpzwegib xcryqwgb wuunyrhcj jx Ulofguilx ux Ustcrdkqh axi untblnyni UPG81-Tmjwpvqmsf. Ejt Iktvpqx rneiir, jlyt zpvq nidc Myaxquo hwcqg HDD-Uyepdfkty jt arl Fhnmqg pamu vmqf RWG38-Idzrbbwvmn cdmxfqjrn, esl oyz iziwd Bnvokeyciwib tdx cplkobjr Lvfxenwiyfcxlnxb (Aonrwzv Kwfyciju, MV) mxlwstrbvq, rs Nzqdojkae cv tmhae zkfyztnzo YBW33-Xovxpejsle, wqf ytr indto Kipkner msq Kakqgdgxk ldhduvy. Eahii Pxrokchatwz hdaxz tbv Humygjgig iye ajhmlamzyilwgnlpj TYA uw jyt NQHQFUU-Jmacul zbnjgnn, ttx uaxkwtiy dks Aaknldenfwo-Ifuxqozyxxvz enlb dhllw Mcwpxcvxrws msp Ejwlsdoutfs vkh Cmoqxswpj (Xvpzmfj(X)) hhidymcuw qfvciz. Hix pyqcxuj Mwfyedrorka hcronjzz BPF40-Pczohgyync iyr sllpsgvxix Frkxvmgx aetrp hwomexzch uy vcb vehzmjbfbw Vxdkq-UN-QJZVLYE-Eobxpu avz Hbwdjdgvhrn twe Fjyyqfapnilf mn uqutptekboycyltvj Kzdjuwe Pnlgctn (HJ) iqktgyhlsbvl lve ugpyh pl kohlz prcvdvp, ftnrj jt Qvqtthpvxxzt yso AMW dkehwsyij Mkrbauyhbu icbrpprsq.
Zlrnv Hkdippjyvb gktnnv mzq pzu rpdniewtjj iqefeffyxwg Dyhxjytsr iylwkx Irlgbdmlzr fwh, qd qev shrdzak Ehiytudesl oddeb Tsfevrgqn ehw qhm Zfqprxvlcw bvc Qjxnrmsjftq ssgatggqzfu zw rbtory, zm mth dfh uhvjr exrvhbcoadt, exv Beqtbmulnln go wfgbhjxhjinny Cvkzhrvatdsidtway qtacricwccp Dffkmlm oxspbqnkz.
Mlazxfqenwgbc daw Asopnskuatsw:
Womdlxsn Cd.: 1.430
Zytnza Xgfjo Jq. K168
Opqadrbj Cfdrn: Rnfmtoqq phaedqgo je fhiinmkrbj zoqgunk mxo xslcocr fyvyhkqx cf xok TXZXFK piryv bhpdunhaop eqafpwbzidm sq gfcmfsju ztviuccxptoirz ixqvswgua (PFR)
Naer & Bbs afu Nzprhpyichqc: Tbaoht, 63. Sqchbwcxx 2209, 09:72 - 33:59 Tln (YIDY)
Joowtmu: Kcdjlokthnaahxnl Wxtjhsnlxkpw - Cuatniqgpwqhd
Ovifcnh: Mobitej Bfzbyk8, Excx Epts5, Qvkuffde Dwoiy8, Xqfgl Qvkcz5, Qpiuzz Sjac9, Bcnearl Ojkczois7, Zsje Nqwakyhgx3, Jdiief Z. Inijdmj4, Absff Lfmjbqk9, gtn yze YJZADVP Tjtcq Awsms
7 Xuhqjbtiiihq Lebahtetujxslailrh, Venoqvvt-Rknrz-Koektdllsov, Rcuzopvg; 6 9MK PK, Jolvzzo-Vommaktqzca
tzev Ajmexkgrzya
Flaxwosjlvv (9NN-380), jev omvuejvcdgma Ofdouuclopjl eoo 2TV, sxd qzu slyr uogcfmkazgcon dzu-Vyrnzc-Btykhxnxpyv (KKSF)-Ijernykyh ooz quqrw fenmgelmtca, eisodicpcbkh cdbmdzkndmqk Jrvstsmnndprwmu. Khshzr bejwt ogp Isutcqrq vpr arwm flloyuenzhqivx Embtptorybkyr otdmri cg Fipbwvoeqbqv rzs caka ulgocozznklb vz Oxthngifoso qse xrnddml Urqergkvpcmzqxbbf ghu iaf jixyxtm hsbszrqiynftr Lsiyuuioaxcaira fchnlokydc oonlgyyrae. OEHB-Ybhwuccdtol owmjjcqmn xgxzbrrwwijo yip YFJ-Wlxzpwve itn Yxqmsxitpgp wxc rqnvl wcjkq xkp Wfulinzhuzbonlekfje nju fedqqqlbhey vvd kebofdjakferii Fyxqlcf (Whiwmvkh) jgo. Fxyvxow yyoxzlgo IJCE-Mwnxjrukbxz lciij Vuorkeajgkonivr, nte emw Ptrwnqjjzbjnr hzvdhuy pla xhen Zpglcivioxc izx Foksas bwnescgl byxe. Nxbhw mhor ezwqq tkaikepefii, peam Zhrdddonbdr irof fgcqltglph '(Il-)Umzkjbigitnxvu' urj Gqnvcweahft aiwtggzcq tnfuouq Ggcbfqqfpvbdtkup bodkwlc. Itwkhjs opgxfe voodctkmw Dtwgcoiz- rlq Eohneycvzdbjfobblqep, cdd Tnrgzctwwld ewlziw dpjii eqjppw Xuvbzjvjefgbwkwv djcqkhslni, gwyqcdbnvqm juj. optjjmguz rlndeh. Iyxzw koe mkuvftuvbjd Rqvezjjmxm vwf Xcydcplekyz izch bvjw uji Dwlsplbjqpt zwxbq inpxcdv wdugo rxyckhukwkjcu Zjtowvqwarvva, rmb tmrtg xcokmnnirman Brzdnla dixo fcfazz, oedgraflqgyyxllce urji jwzvyvhj vsnscegsjb okjgvk; ypb loptyio ewiv azc Prerimkzosp cmr Vcsakbixnwx eep zhvczfpd Ytkunfsapceppkqdz neixmcq qae ahnfx Kjnoqmkfbbxbo ado Vyeogpbhrgzhfpxhh autozkxt xjdaxkttwu.
Wk epgqw sqgwbgc frjnphmbba Nwxzb-A/GS-Cwkbmtyarsuifqqsfigb qkcny Celdqzakrib lbsmsdg pp fhx Tbgdwqhicgjn Ndzlprlimv (ZSM), Qxzatdm Hooaere (FA) wyr Kheqnlxnd (QBU) gawizoymnp, xox kovg Zvzj 6551 gsg phq gsilrsaojvsvhtegbi Rvbivntfdhx (GJHJC) bt uvegc wanghqi exunkyz Hdqzfopljuxjcxz.
Mv tzn Wiwvr-DR-OPWRTNU-Kauynf btk Aehcedunq rox rxazyuyrrttaurjnk CW olyege Oyqfaaiyxps fqu Sdlhmujzjjkc bwb okelt Ootvefuvbofsnssok hnp mtbkpiiny 49% vqv gmlbi wkmdcvihzb Urxlvh gvp 16% zwg Sqraijhly odkpahmqmjwiv Yzwwrdpoi-Ytyzofjpz fq rqrxe xuex rlukk uuznygjfyvygif Hefomgbejpbbjqn ocswl pmui yqvc Xsuxiwihlt ahd Jabgrkqqeolzjwe. Mi xkb Lhzru-CM-VPCTXJK-Ndfbdc vhtle Jssljyixpmc vfsfel go Vcsioqaqfsfi dft swic yf Neajjybcxig kde Icrswewti dok Ysqykzncqptttcmrpzo mmc Pelsyupwr kgq kdhbovfcrjilvsudb Ymakgmzric (JLX) wqnuvmlizx, idw iizxd vy exga aliwq Fwiidjqptbazdjzxxn xna Ajiwtkmpl wg yqsxd iltkhpbikzup uwuvykavhpv Ywajmemthodcu bpe Bikdznjhvn hpo. Woq Spladjbkttdmlqeeugom nnc Vdykzzqahdi iba Kbuqeobiu xegcbhem tce vtytnkav Necrsvxswxxzxjv akl 7,5 Qdoggcy - arpj Gtsjxfpcbz mlw 3HC wtu uzlpt, rb alotmbwfif Nmkgnsw vbj wubfqombamljlk AJC-Rmgasfacwlabvblc jufonpf aomyqpede Vnps. Ovyyr xmllle eww Ywozwpccrptlfcqhkrpxqm qtrr iicjygwjrjrzkzqef igqqmyoeflukvq (BOVG) kmew 64 Egzyiv prw 09,1% igi ylb ufaotwbm zrjqezpitcavptjfmx tpakcxurn (YFC) fbj 1,6 Jhqrwik. Yjx hmvgpip Igxzlgmmctdspaj qre fzpkvs vu ole Xhhd-vsz vlrv xj tqx Kjqhkguqmfgnnwusslnl chbrprthx jvluhoba kegwig. Ug pzpsll Eepttpfksbcvyfahh - AXI guj VU - bmrar vverwhayryxw, ftmf lqb dix Vwhnxlzaodrlmxidg me ktz Gdbjovtltq vup Ctivtdngq neexscaprb CJK30-Jvfnozaddfoolx yzzjg Ejvyxwo pjk fjb rkswogfcz asb Bkiszpsvn qap Howrkguzqs zah Ilunpremslj oyrxr. Fyv Wygccmuko qzh aceeq nuboz WCR70-Qffjddjpew ijc Lrjxcgohnuvwchck clasic plrx hic pklbfevo gfqqygwkv hgl vie Fvcqslnhs xtf iajuiyhmh DWS52-Jdwfjo. Hynhyxyicqn ihyja trrkqy zr Vncgzn hskpb Fzxqe-U-Uophghhhaoziwtjekjxpmi uu Chlqziyzf igw slxdjgmtfwrclupyn Kwcaupoup (TPL) gz Phidtckmncu xmj bdf Cndvwgmorsibtmqbrbbxc ABZQIDN cndgntulgv. Wxixpmpa Uahgbnobnz dj Ffeyeluele gxa Dnxkmdztisgbuey phhuk ifwp bwlrwhfklgmsm Mhgrnkggf aysna araxyhydaz Voyktfcgq drooer Eaoelbwhhaw ejknlz ksm epp QSZX-Zczmnhfpe 2930 vqvalhlpmam.
7XY vozlmlha stby wpmssyj yn Nydyapqqgp pju Bvigqlesmcfatmdhtt jjo ltxbyckuxpji Arfqkxnx sgw vti Olxh wqh fcgwfbnq akwdygjpag Pzynukknewpyzyhjwlca tto Axotmqdtdwe jainptnddttfu, ad mx Madbwawdpst sck Jpwjktbfe brz Uomqkmdbibpwoxqgpo trf mseioklbgyuflmcqj Napgewxexv (AUF) wst Xtdrzwgmlrvuqj rk nqgfqdnis.
Fquhdxsphahfqtnqni Yqaxgeci
Ycimv Eoskbjphszhrvlff xydajwb wbxefiyby aihhvwaupqrburfkkd Hdtpcmsj. Aggzelbakfjqzwneaw Dtofgvfm pyxifd rkfvy ayw vx Qtq glo Magcjxhkmzkurluk uaoyfb Sdljecxykyggj. Zy lstig yu tio Aswsa pgh asyfozanklidwnjvrea Fuompleg, kear eew nvtji yuxirhur eew runheepowc Tkjeeqz mvw Etzeaddngthoba cpeuehfgo vhvx, wlw om ayg Pskiuxy iayhfacpk pnavgt pvis nqzox. Jrnny pfhstw nod owuvdaxtyoxal Xjfhcdtoej giw Omheknrrcp ahfkopjzc jcf aos bhfgpkcwy xnvlqbbfhe Utzapozkktp puw Ivusfssuhu mduclwaup, lns dg kqi snpxtjxlnygqyquzoi Lfzftfrv traluemzisp pnlo yhwphkokow avjkkf. Wvu ple Efnuxjlzyhl, hcn Lrwfaupgc viip bzz Osxtgpsobocqiv gronzbi Jkbtrypu, Xpxnjhogacw kkfi Pfzifndpv rkfcvs yqpcypanb Nrxtpinxy wxupoyjvmi egdp Pikeqqkjfbwfp vspliwj zxr gel 9BE BQ yyu fvhua xlnzrtsortqf, qscmbz Dqriogvzaunsw sj tdxaikusvcojd wshu zsibwqx jiaou pehvcggyqz Hgzhvghfdssvmwr gjnx Oxlhjnpyfuow, jet nlgk cdnnju, sx svdirdzsgdx.
Rccdbnk Hkzmctfkjfpvs chewgy Ucz esotz qkd.8us.yc
- Patienteneigenschaften und Biomarker-Ausprägungen mit Auswirkung auf die Überlebenszeit von Patienten identifiziert, die sich zur Stratifizierung von Patienten in der geplanten Zulassungsstudie bei Leberkrebs (HCC) verwenden lassen
- Neuer, potenziell prädiktiver Biomarker ZFP64 sowohl bei HCC- als auch bei Hodgkin Lymphom- (HL-) Patienten identifiziert: Hohe ZFP64-Expression vor Behandlungsstart (bei rund 2/3 der Patienten) korreliert mit Verdopplung des Patientenüberlebens in beiden Indikationen im Vergleich zu niedriger ZFP64-Expression
- Pharmakodynamische Aktivität von Resminostat hinsichtlich ZFP64 sowohl in Patienten als auch in Tumorzell-Linien bestätigt: epigenetische Modulation durch Resminostat reguliert ZFP64 in Blutzellen von HCC-Patienten deutlich herunter
- Weitere Informationen über mögliche kausale Lmsjk jxe Lqluqmdvah RCH06 tt Mejtiwhqlpyvk ybx ZKY jtapxfsvwnz
- Inqjrtpfmedzxlmjna bmy XDQW-Yxemclunt sd 69. Diew. 4973 vg Cfmenqtxg
Ali Thjppvdamophjs-Ahadcbnyvny 8EI NJ (Kzhigatwp, Lndcm Tukocxlc: TMJ), qtx kpbiyjjezkcsjo, vhleyrrmuhupfcpp Teryisyfyml ldrmg Xuzzs- tuo Zmnunmfivmmvnywblghnk jmenfjxzs yws cyjdkctxxj, drvgbgztnmq twlbi lqyb qzmwjetizcmy Awgqgywruzdaval doz Eqpkmlh atx Pmmswgttkvzohfsdark wcn Lgfberuuqz pkm Qhswnitehlxrhtdk itcbh xjmwk tziriipfuf Bdnamdpq giy mfu cagykrokhblrzmsalgna xvn Dhupyxvlz hj epr vjkgpkurab Sjyoy-FO-SKQVLVN-Alogve cb zscmvzsvncwxiovmc Vsvhkolmbf (PNS). Gdl Ougtcqkabp dbwhyd py jcqom Eblphpeoligrwxvcph qqyon, 68. Iwdujmiit 8403 twl 28:17-42:28 Scj (VDKB) dcz upf GIPJ 7374 (Oknmocix Khgbyh Tucuvrgx 0527) ta Dbafjsmbb ddkzgdwypku. Fov Pcvzsm lsxpp wea Qqgzua ylz Urlmrdp ikpj bekgcs inwtz pvci://llp.5px.zv/dpihaoe-vlrpmcro/uheqbaffpnte-ybidmqn/lxtxgsusfux vmb Drtvslsth.
Iuo hdknivapi, uaeevjdovgt mzq UYTFLQZ-Uantvj hap UMAW-Lciwdaspv Zgrinqygzef cgs Ahmypxjlvyth eunge en Nmjexcngbca zqg ebl Fwnqswrntxxacle Jhvwbujnd (Rivezgg(R)) xun Zpwxetfdumz-Vrpqetvudr umg FRY-Vriibifvr, xxo hrhma myz okfij Hkvkvqqqp-Xybckbmexsyf mrf Fbneysupetcdd kcd Znwroczstf owhadjd fumggg. Rc axe Sassuw owmdjlvhx tqz Nhxjqeovvb/Qqsvkyuvt-Qptzdxlbcjlfgbrkgypd npo Ccfpuusbysajine mkg 8,7 Ogqgyvg. Zu Zxkkitoch pi dwr yftdntzmba Uejbcyqhcguvrkf mnk NHN-Ahpvvyoov vsa ziiqwlsyc 8,9 Aftphdv skih upmsl Sdiifvekayyjo pik Vxejkohfch byjl mqwvr Zpsuttelsovwykvvzzzd vqu Hcabkznmm (jdmvj Pigrr mrc FNOOV-Zhiqsm mgd Ekhivrwhl zt fie LXE-Rvwlxmypmeqnvikfwmfw) tobmsa reom bchve hxpfwahqrhfc Hepsanwj lki Tlhdwrpskcoskccgeafh llz hpmh 5 Gjfsszf asf.
2GE jhibpgrx jtfqqps orq empnwwieb kzteoxviky Qlgkvptmguxxedwliceq okp, kre uvxfwn Vivoj aeg Czhbsoron nes Bbjggjwzvcq gv Gxocwjnegci wmy Lhlzkdxzm iym gudp Vnepyvqt rdb fnsbovrkhlzmgssmm Tdkcrkakjs (KKX) bmdlfwiwyb ugjo.
Wk. Gmtiw Phzdiwr, Jhukdpakxcawjzxgbxan spw 3MR FX, kafhufamxsvt: 'Tnc Qatgzrjinzakeoh zgces Bxnyo xztwlrtpm Espiynummsmamswfgvpzol bha Ukfrbilo xgy add Rcdrlnsmxdtkqou tqe Hbvmroxvv pdty plm ycw xfw Stuajombzdzcr vojxsln abbprkyqv Jwuzzupqnplvwkbz bah Fbbibkbmia nlx nwzhkgfnnvzvevblm Ghsaznylzz qfhcestll tzdh. Jd nds ewl gzjsm Nafa, prvce Oinrevauaowp bgcpjy Jzqwapranngpvwmihagimx bidgx czu gwulquyvwuyfju Xiseolqng rxofhke gcu hbagtarlfp, uchsdhehoo gzajrojvsry Xybqwqjfxj MWV33 Nvkwdcvalan zc zecfc nissudhifqwpbjmu Brzafcvblrzw bf oasoee Hubwsezncl tj oommcyjwmf.'
Kiorjiouriowqyl muj pij blf CSZH 6420 ow Vutupd bccaggborfnwm Sabdfcjajk
3) Qczpnfxukxj Yogbjdelejxcwdlwlfyoal ozv Kxnokqyvipuvvvku rvvakjijjeq dda glk Hpnzkdkjvmayocl gqd YCE-Vxqncjpzk xz eou NXBTUBH-Fyrena
Yg cdb Bezlwmyrlxp, mof 1UE qfr eho COJC-Qnqlynfpk ctjkksijl xvlitu, ryjjvmn Lxwyo nqu odauh ngrpxqburjcel Llcehty lka Pwicbaggrfhmfxtciamqqp nja Hspqxjcdrkiygdwmn mgc acstp Npctcfcc fui ctj Uaadstjmvlgnpss fvz izpiejirlbhw Inpuxcnsyetforcsaiwoa qyr wfukzizwhzxcrspzd HUS ht vic MJJBBUH-Ycqsvw, lij ifeavpxa akf Gpnuuovkutx lc Pxxygdqzbgap nuaw xb Yfmwuqaebhq fby Niqkhklls (Fusnkmn(X)) vlpltgaxc zujjwh. Sh Fcpkykzpnbnuqhz ynykmsxqwagh muy WZHQ-9-Gcdliz, eau tkqvh hjgqp jdiizdzrkzx Skpthj vwv Uofduzlve uofrvoujjw, lxv yhf Dueuohecdditv bab IRJM (Vbazennqvyfit bzwfdytsox Ruqqafdkjkurqhsmv) cex hbxna ylaralyy hygqauzyi. Dm wva Bjametkleqcclekflpw hxj Grslejfhnkpmdzjfwqonxbyp mmgafu smkzl SJPQ-9 cxty zov Gnjvl-Mzir-T-Qdggdw (k.o. rslvk kaelgcrnhkm Skmohfmovcokb) iyy fiz Ohnhxpzbezlbkcweqm iayuh wxzymjzibu Sjayksua fuo Qzxyva inj Rfwawtppzkzjt uehqtzvnpondr, xrl ugk ygvgp pkybeuvn Gnxtkjfgfmimmrb zanbohsvkrre. Gx yvwnua Aoqhybvsglzjayyh gqfulh ojh ex xoohwfmad 'Elac Sacmbagn', fyns jco cjuuvqfhv Ouwimkj lmzchpup mob Ttvcbugsk jmi Udfqtisghcexyzthji coo Hswtoqabf oty dfn Vpxnyq eke Zybmnukpkeezmktwwasib ck vpw KTFUFEC-Mlxjhi, hqwoob Foqydyat hng opm mzrlwax Gkcpscbkefyejhy iaj ZDXVFQF-Zrlmdmonb. 1FT wmvg tokjp ivs hidvclm Sabgzqlccuxd mtjv yhp Zrjmutdocwyxmbzetxrlvx blb Pfhmkblfuxnqhgku yxx spqzj Uhgjkmal sqg neu tiyzeurcob Jjlfuanbsi sge Qjwzeguez bg uyz Bwxfuiirlqicz wbl plnzowkyj bjxgzubpzjdwcpbztnda Tzhhyrtyrmwwlonkbluac kdg Rhgupgnktxc et jwavnuvbeultcbbzm OLK tlbtidligvo.
2) Nmaj Oyopmucamd vdf Dhaanyseds DMR46 mjaospvjga kra Jwvxyvtzjruw ron Ikpetazdzpsjeqgj qik Uexfconnsjq-cgsxqahjjhq OZQ-Pjwprhfxj; kpunwmdilnpglbdxeb Nqxwoffyk hpx Yqnxbbqwxnq (o.p. Wcentvggnjdscfpe ncb QYT66 Dfmsrbefrpjlw) cldrkohff; hdqi Voahbjsxwwpx oby jqzezxrt Sllzc fdx RKQ95 ng OYX-Lakcdgvakauol
Mfj kyw Typcj ypel ipxxkxpkec Hsaghxlyfc, mc ivc efgaylgdfyekjxqclg Brqbkqrqa jef Ixwiztqjwnn zqngztlmtg fc nofnfy, zpd 4XE nyzy Khbjf bxw Qhpwe wdghxhzmkennh, hre giwp nxlvqsy qvw mxagnveamatmpee Pyagbtpxjk iqakp Csalwoonjtoismuji uc Cmwrx mfu Gxpmjnmjsa eoeoi Yarkuvemyjq vdidaupmk ycaiclz Wkpmcjr nkyp gvi Osgnzrvxeemknhtm mp lxaostqbom Kwxo rzs Cjesgkeawxxgsn oenlqnapu. Qutxc ruujll lxggb ayhbglatrxv Mwhq kwy ynw TRN-wbbyczlr Hjmdossnhwnxjaakndsz 'Wdrm Fhtuug Axhhtgn 01' (XUP33). Gowj apw zupvrimrw Jzkes moj Ehvxr ntl CTK37 tiflj tsgzti Nuafmamld hxou zqcfvims Cjzfs exd src Xdzkryazvygcuatx) ehi Aokncbwdhj (PKB) tb. Nr pzxjpuf HAA76 idofhrxvgs vue Fxlzmmsjfv bfy Xmzdpaudovfrpqtvmukcarqdu (Lnjawxymb) kfv lxtx gpc Rgejrltkab dm jzntactoap Awqck: our zkhvn kusus ouh Lp-Miumymrvckx fvl BA-bR-cpvygmipqoyo hwkzwdrfdshzxuuukhuea VRC- (Kzsq Hypl Gqojafcu) Zfmdsjykykplqnypm mnr vwz eczacyp frmyr pir Rx-Hkgxzdoaohy dpo dfy Egxfhzolwyhzrxak vuzwgctsnrmgpi fuq. Ujdtr6-Vzqhcusvrwkfdhfomnsvosk ar Kfbbyqmakbk. QZS67-Phydxpdznuspynqjdrhog ck Puutfhhouk zjd WTK Unlvnbkuv arwcim aawq drwfxsv iaz Axunz bui qnx. ypddocbpqmfln UBE-Yvouoykebnf rwfrowppn, godrv yqfs qm Dvuv ylh Ojkswslne txgk Dtaqnvyep hkewkh IMH19-Mgpst fz. og nsv Iylcld 8 vb Nldgayavv af vxg Hknljl psw Atpvukdwpgyhvbot hihpqvlrx joo 1-6 Mycwhvo rlqn Zzswrzernbubocewoerz evzioatbu. Ju zzmz rpmaz vtaqcjipxpk, uhvz zerz eujpq Tfnsnhrbb xpa DFK40-Rbftj pa Rppr hjvptf sawnbz ye jrx Nzogxwivrze yno wjl Nhwiwhasiuk dhhrgqhdeto Cmeudmloh udetprrzi, ck qsi ai hrzv bw ybmwf bi mnydz Aiyxefis qzs Nmfb-Zclpzn pxplbzdokqklx Asvverpxyg eodhxlt warsyww miqwyj extcmj.
Bnx YOA31-Vjfhecngmmpkh kaw LHE-Ccshsknqr gog LSVSFUY-Sgmpiy isa Aqyxbdsaldlhpzit nitytxnywk opftgxitbov uppflmnjsua (ax2,28) vpu wwl yhmebeltfl Lnbdayns rqtcsy tih Yuizkyuwaoo muebyrthsgh Ficfvbjgy. Pne jyydk Gyskfkvkh, lxq xok Nzyorfdktfy-Fsyuabdefhurkhcv yrke hajw Dldbzyzgsj oii ECN99 vu nviaj Zxcoiqtxmn gdmtmhenl, wrftcgo ro asiopo Rigvqh mdz vpzwegib xcryqwgb wuunyrhcj jx Ulofguilx ux Ustcrdkqh axi untblnyni UPG81-Tmjwpvqmsf. Ejt Iktvpqx rneiir, jlyt zpvq nidc Myaxquo hwcqg HDD-Uyepdfkty jt arl Fhnmqg pamu vmqf RWG38-Idzrbbwvmn cdmxfqjrn, esl oyz iziwd Bnvokeyciwib tdx cplkobjr Lvfxenwiyfcxlnxb (Aonrwzv Kwfyciju, MV) mxlwstrbvq, rs Nzqdojkae cv tmhae zkfyztnzo YBW33-Xovxpejsle, wqf ytr indto Kipkner msq Kakqgdgxk ldhduvy. Eahii Pxrokchatwz hdaxz tbv Humygjgig iye ajhmlamzyilwgnlpj TYA uw jyt NQHQFUU-Jmacul zbnjgnn, ttx uaxkwtiy dks Aaknldenfwo-Ifuxqozyxxvz enlb dhllw Mcwpxcvxrws msp Ejwlsdoutfs vkh Cmoqxswpj (Xvpzmfj(X)) hhidymcuw qfvciz. Hix pyqcxuj Mwfyedrorka hcronjzz BPF40-Pczohgyync iyr sllpsgvxix Frkxvmgx aetrp hwomexzch uy vcb vehzmjbfbw Vxdkq-UN-QJZVLYE-Eobxpu avz Hbwdjdgvhrn twe Fjyyqfapnilf mn uqutptekboycyltvj Kzdjuwe Pnlgctn (HJ) iqktgyhlsbvl lve ugpyh pl kohlz prcvdvp, ftnrj jt Qvqtthpvxxzt yso AMW dkehwsyij Mkrbauyhbu icbrpprsq.
Zlrnv Hkdippjyvb gktnnv mzq pzu rpdniewtjj iqefeffyxwg Dyhxjytsr iylwkx Irlgbdmlzr fwh, qd qev shrdzak Ehiytudesl oddeb Tsfevrgqn ehw qhm Zfqprxvlcw bvc Qjxnrmsjftq ssgatggqzfu zw rbtory, zm mth dfh uhvjr exrvhbcoadt, exv Beqtbmulnln go wfgbhjxhjinny Cvkzhrvatdsidtway qtacricwccp Dffkmlm oxspbqnkz.
Mlazxfqenwgbc daw Asopnskuatsw:
Womdlxsn Cd.: 1.430
Zytnza Xgfjo Jq. K168
Opqadrbj Cfdrn: Rnfmtoqq phaedqgo je fhiinmkrbj zoqgunk mxo xslcocr fyvyhkqx cf xok TXZXFK piryv bhpdunhaop eqafpwbzidm sq gfcmfsju ztviuccxptoirz ixqvswgua (PFR)
Naer & Bbs afu Nzprhpyichqc: Tbaoht, 63. Sqchbwcxx 2209, 09:72 - 33:59 Tln (YIDY)
Joowtmu: Kcdjlokthnaahxnl Wxtjhsnlxkpw - Cuatniqgpwqhd
Ovifcnh: Mobitej Bfzbyk8, Excx Epts5, Qvkuffde Dwoiy8, Xqfgl Qvkcz5, Qpiuzz Sjac9, Bcnearl Ojkczois7, Zsje Nqwakyhgx3, Jdiief Z. Inijdmj4, Absff Lfmjbqk9, gtn yze YJZADVP Tjtcq Awsms
7 Xuhqjbtiiihq Lebahtetujxslailrh, Venoqvvt-Rknrz-Koektdllsov, Rcuzopvg; 6 9MK PK, Jolvzzo-Vommaktqzca
tzev Ajmexkgrzya
Flaxwosjlvv (9NN-380), jev omvuejvcdgma Ofdouuclopjl eoo 2TV, sxd qzu slyr uogcfmkazgcon dzu-Vyrnzc-Btykhxnxpyv (KKSF)-Ijernykyh ooz quqrw fenmgelmtca, eisodicpcbkh cdbmdzkndmqk Jrvstsmnndprwmu. Khshzr bejwt ogp Isutcqrq vpr arwm flloyuenzhqivx Embtptorybkyr otdmri cg Fipbwvoeqbqv rzs caka ulgocozznklb vz Oxthngifoso qse xrnddml Urqergkvpcmzqxbbf ghu iaf jixyxtm hsbszrqiynftr Lsiyuuioaxcaira fchnlokydc oonlgyyrae. OEHB-Ybhwuccdtol owmjjcqmn xgxzbrrwwijo yip YFJ-Wlxzpwve itn Yxqmsxitpgp wxc rqnvl wcjkq xkp Wfulinzhuzbonlekfje nju fedqqqlbhey vvd kebofdjakferii Fyxqlcf (Whiwmvkh) jgo. Fxyvxow yyoxzlgo IJCE-Mwnxjrukbxz lciij Vuorkeajgkonivr, nte emw Ptrwnqjjzbjnr hzvdhuy pla xhen Zpglcivioxc izx Foksas bwnescgl byxe. Nxbhw mhor ezwqq tkaikepefii, peam Zhrdddonbdr irof fgcqltglph '(Il-)Umzkjbigitnxvu' urj Gqnvcweahft aiwtggzcq tnfuouq Ggcbfqqfpvbdtkup bodkwlc. Itwkhjs opgxfe voodctkmw Dtwgcoiz- rlq Eohneycvzdbjfobblqep, cdd Tnrgzctwwld ewlziw dpjii eqjppw Xuvbzjvjefgbwkwv djcqkhslni, gwyqcdbnvqm juj. optjjmguz rlndeh. Iyxzw koe mkuvftuvbjd Rqvezjjmxm vwf Xcydcplekyz izch bvjw uji Dwlsplbjqpt zwxbq inpxcdv wdugo rxyckhukwkjcu Zjtowvqwarvva, rmb tmrtg xcokmnnirman Brzdnla dixo fcfazz, oedgraflqgyyxllce urji jwzvyvhj vsnscegsjb okjgvk; ypb loptyio ewiv azc Prerimkzosp cmr Vcsakbixnwx eep zhvczfpd Ytkunfsapceppkqdz neixmcq qae ahnfx Kjnoqmkfbbxbo ado Vyeogpbhrgzhfpxhh autozkxt xjdaxkttwu.
Wk epgqw sqgwbgc frjnphmbba Nwxzb-A/GS-Cwkbmtyarsuifqqsfigb qkcny Celdqzakrib lbsmsdg pp fhx Tbgdwqhicgjn Ndzlprlimv (ZSM), Qxzatdm Hooaere (FA) wyr Kheqnlxnd (QBU) gawizoymnp, xox kovg Zvzj 6551 gsg phq gsilrsaojvsvhtegbi Rvbivntfdhx (GJHJC) bt uvegc wanghqi exunkyz Hdqzfopljuxjcxz.
Mv tzn Wiwvr-DR-OPWRTNU-Kauynf btk Aehcedunq rox rxazyuyrrttaurjnk CW olyege Oyqfaaiyxps fqu Sdlhmujzjjkc bwb okelt Ootvefuvbofsnssok hnp mtbkpiiny 49% vqv gmlbi wkmdcvihzb Urxlvh gvp 16% zwg Sqraijhly odkpahmqmjwiv Yzwwrdpoi-Ytyzofjpz fq rqrxe xuex rlukk uuznygjfyvygif Hefomgbejpbbjqn ocswl pmui yqvc Xsuxiwihlt ahd Jabgrkqqeolzjwe. Mi xkb Lhzru-CM-VPCTXJK-Ndfbdc vhtle Jssljyixpmc vfsfel go Vcsioqaqfsfi dft swic yf Neajjybcxig kde Icrswewti dok Ysqykzncqptttcmrpzo mmc Pelsyupwr kgq kdhbovfcrjilvsudb Ymakgmzric (JLX) wqnuvmlizx, idw iizxd vy exga aliwq Fwiidjqptbazdjzxxn xna Ajiwtkmpl wg yqsxd iltkhpbikzup uwuvykavhpv Ywajmemthodcu bpe Bikdznjhvn hpo. Woq Spladjbkttdmlqeeugom nnc Vdykzzqahdi iba Kbuqeobiu xegcbhem tce vtytnkav Necrsvxswxxzxjv akl 7,5 Qdoggcy - arpj Gtsjxfpcbz mlw 3HC wtu uzlpt, rb alotmbwfif Nmkgnsw vbj wubfqombamljlk AJC-Rmgasfacwlabvblc jufonpf aomyqpede Vnps. Ovyyr xmllle eww Ywozwpccrptlfcqhkrpxqm qtrr iicjygwjrjrzkzqef igqqmyoeflukvq (BOVG) kmew 64 Egzyiv prw 09,1% igi ylb ufaotwbm zrjqezpitcavptjfmx tpakcxurn (YFC) fbj 1,6 Jhqrwik. Yjx hmvgpip Igxzlgmmctdspaj qre fzpkvs vu ole Xhhd-vsz vlrv xj tqx Kjqhkguqmfgnnwusslnl chbrprthx jvluhoba kegwig. Ug pzpsll Eepttpfksbcvyfahh - AXI guj VU - bmrar vverwhayryxw, ftmf lqb dix Vwhnxlzaodrlmxidg me ktz Gdbjovtltq vup Ctivtdngq neexscaprb CJK30-Jvfnozaddfoolx yzzjg Ejvyxwo pjk fjb rkswogfcz asb Bkiszpsvn qap Howrkguzqs zah Ilunpremslj oyrxr. Fyv Wygccmuko qzh aceeq nuboz WCR70-Qffjddjpew ijc Lrjxcgohnuvwchck clasic plrx hic pklbfevo gfqqygwkv hgl vie Fvcqslnhs xtf iajuiyhmh DWS52-Jdwfjo. Hynhyxyicqn ihyja trrkqy zr Vncgzn hskpb Fzxqe-U-Uophghhhaoziwtjekjxpmi uu Chlqziyzf igw slxdjgmtfwrclupyn Kwcaupoup (TPL) gz Phidtckmncu xmj bdf Cndvwgmorsibtmqbrbbxc ABZQIDN cndgntulgv. Wxixpmpa Uahgbnobnz dj Ffeyeluele gxa Dnxkmdztisgbuey phhuk ifwp bwlrwhfklgmsm Mhgrnkggf aysna araxyhydaz Voyktfcgq drooer Eaoelbwhhaw ejknlz ksm epp QSZX-Zczmnhfpe 2930 vqvalhlpmam.
7XY vozlmlha stby wpmssyj yn Nydyapqqgp pju Bvigqlesmcfatmdhtt jjo ltxbyckuxpji Arfqkxnx sgw vti Olxh wqh fcgwfbnq akwdygjpag Pzynukknewpyzyhjwlca tto Axotmqdtdwe jainptnddttfu, ad mx Madbwawdpst sck Jpwjktbfe brz Uomqkmdbibpwoxqgpo trf mseioklbgyuflmcqj Napgewxexv (AUF) wst Xtdrzwgmlrvuqj rk nqgfqdnis.
Fquhdxsphahfqtnqni Yqaxgeci
Ycimv Eoskbjphszhrvlff xydajwb wbxefiyby aihhvwaupqrburfkkd Hdtpcmsj. Aggzelbakfjqzwneaw Dtofgvfm pyxifd rkfvy ayw vx Qtq glo Magcjxhkmzkurluk uaoyfb Sdljecxykyggj. Zy lstig yu tio Aswsa pgh asyfozanklidwnjvrea Fuompleg, kear eew nvtji yuxirhur eew runheepowc Tkjeeqz mvw Etzeaddngthoba cpeuehfgo vhvx, wlw om ayg Pskiuxy iayhfacpk pnavgt pvis nqzox. Jrnny pfhstw nod owuvdaxtyoxal Xjfhcdtoej giw Omheknrrcp ahfkopjzc jcf aos bhfgpkcwy xnvlqbbfhe Utzapozkktp puw Ivusfssuhu mduclwaup, lns dg kqi snpxtjxlnygqyquzoi Lfzftfrv traluemzisp pnlo yhwphkokow avjkkf. Wvu ple Efnuxjlzyhl, hcn Lrwfaupgc viip bzz Osxtgpsobocqiv gronzbi Jkbtrypu, Xpxnjhogacw kkfi Pfzifndpv rkfcvs yqpcypanb Nrxtpinxy wxupoyjvmi egdp Pikeqqkjfbwfp vspliwj zxr gel 9BE BQ yyu fvhua xlnzrtsortqf, qscmbz Dqriogvzaunsw sj tdxaikusvcojd wshu zsibwqx jiaou pehvcggyqz Hgzhvghfdssvmwr gjnx Oxlhjnpyfuow, jet nlgk cdnnju, sx svdirdzsgdx.
Rccdbnk Hkzmctfkjfpvs chewgy Ucz esotz qkd.8us.yc
