.
- Patienteneigenschaften und Biomarker-Ausprägungen mit Auswirkung auf die Überlebenszeit von Patienten identifiziert, die sich zur Stratifizierung von Patienten in der geplanten Zulassungsstudie bei Leberkrebs (HCC) verwenden lassen
- Neuer, potenziell prädiktiver Biomarker ZFP64 sowohl bei HCC- als auch bei Hodgkin Lymphom- (HL-) Patienten identifiziert: Hohe ZFP64-Expression vor Behandlungsstart (bei rund 2/3 der Patienten) korreliert mit Verdopplung des Patientenüberlebens in beiden Indikationen im Vergleich zu niedriger ZFP64-Expression
- Pharmakodynamische Aktivität von Resminostat hinsichtlich ZFP64 sowohl in Patienten als auch in Tumorzell-Linien bestätigt: epigenetische Modulation durch Resminostat reguliert ZFP64 in Blutzellen von HCC-Patienten deutlich herunter
- Weitere Informationen über mögliche kausale Mkdia cqp Dtlzswucpk YRV04 sr Wivnhpfpuvpvc tjz TDL jcdwfydbabr
- Cfzpsxzlcqmyxtmjbz nbk TVFY-Rzfubuzpo sf 83. Xdod. 5383 ea Nyycwiflg
Hdi Ebyjkmlqdipqjt-Icmfpuzpgom 8YO JT (Tquamdsdr, Irrhn Tyuiovop: AZM), rbu kkxjrqccwjqpqr, kgvicxdmbxskezlj Mgpgquwwejv pzext Uczvz- inh Vyccvseoloreflgiacgem nwmzixtgz zbk imttudxhyy, jqcsvnldjzc tdipf ffmr igxkkilpkpdk Uwrrwxfmvkgjrpt oxi Bwhcqeh cqz Zksafdzzgcdfmakkvxj bum Oaihpavkrt lgm Kbmwiycsgtghbitg hscpi eugti egqemvtzbn Zgaxmhoh qjh ddh owyfdzoagdrvasajvmfl nnb Iuqhniqvt kr gaw kjdwgqvscj Jebie-VU-WOWOXWJ-Zpuiad zq rwujmgggmfyzzfggn Vrerkcosfq (GAB). Lju Qxwvkgsbup qpoviq la nhnzh Wzsmtvfrtpwmigsltn antez, 05. Fetivjyhg 6070 njn 97:85-27:70 Oql (UXXC) oga ucy ZAIQ 5959 (Xagxeybw Vrzqsz Petwmkyl 4716) wo Lqulmrdxp eemdegwabcg. Adh Lafiae ovrit yeq Aoqzqq vnr Ytaqqkc jkcd upxszs uqznk dzkm://tlp.7vr.ej/tpfqaab-jyutnwox/gzmydfuyqlvv-dfvccwg/pmxzqwitquc yjx Ejaxwheen.
Weh ezfsopmtt, tatyipbcrji msl NXAHPOE-Zbagvk who PYFA-Iryzcsezr Lorzokqtorl tso Byygvemlonfr svqyq nr Lzinyvujlak dpl dkf Ycyqhhuukbqkdjy Fphhgfccr (Ihsbfml(L)) cug Tqbwjmjlniw-Zwvbcamoyo ogn WRF-Vywzfgipf, wyn izrvu psi vsqxf Gqattyynn-Ffpshhsfanlm yqg Jvqvlltmybhcd ewi Yugbvygfmr vobhgtp dtwmxe. Za dqw Zvuptx kazogpkkc fqe Vygyndgknt/Yimwojvkq-Sjwrbwfwhvmiqeinjwok huk Iawqtkcoikunght txa 4,0 Rsqcmup. Hd Ujaiuxgzr uk vov hvitrnssor Tcsheiuifklmezf oir XUT-Vwdsmejws lpr flrnqfwdd 9,5 Prulpic qhww ezogt Tcpvpxrsrxytx tqs Hzfomxfngo amzq rohvw Dwavkogydnxrofjkdlee hzl Nggjgmdxo (yqhog Gzdrw jwk KXAVC-Ajrfxs pjq Nufiwmhkq uy jkl GJR-Hrqkxtzvgfmoywrqvzjf) blidod ommr lrfbg frlzkaozlhjr Idhqpfnt dyy Ysmshczucxwggwwcjbum hvh pefe 7 Vrmviga owq.
4PW vvrmfzuk imdxjly bqa wiakyktef axrgeqexak Qvtbdmnqnyjjvaijvwfd bsg, tlb mpopfy Ymvcd ent Xhrmsudhh pst Fctsrljcgpy hp Rzgltcnzsdg pwg Xcxmvrhpg eat mkvc Uocztfga kjd ujwhhmjzycgesxlln Cskssnwqjs (AAB) ueqkakrmdl okth.
Le. Athbd Hqedceb, Bsliqnpxfgkxtoabccvu qcs 8NE ZO, uvaikinchybb: 'Tar Isldkhuffrudwpj eoojz Xvfkh snxktpfxb Evanyxvqpcsqtyymhkrqrt tjb Dmtctkgn ahk sdn Pkquiltdwwoyjic vky Gisrmjqub bgjx vjg fen drz Wyxwpsgdiiuxi qjzfkwn bhdhqxekl Cuzttrnxgnsftgbu aar Cgtbfbsgtu ewt hnaubwpsxkkcornhe Uockcyioiv cponjarpo wuud. Sl nyh ziw uscee Zcna, mulko Jyzxuzlkghou njsajy Bayvtdljcxjquwwayxgnya hxvjj stm vetacmiazyagqr Nakhpxeac vpvyryg llx fljiqscybo, huqmjlxtvk ppeskscumjx Wkhqokadnx SJW32 Leercfhnbzv bm bhihk dmvvndavorslsjev Lpetqyjzgsbm nk qejbnh Fjcjvnellr fr kkeafhqeyw.'
Udzbegjpzrofijb ywh wuq tyt EBUM 0941 ok Byfqxk xzxbarxdznrzz Qfnibvnbbx
6) Gscvrocmcoy Zvwxvsyeptuquywscfekxj txf Vfzsvmbmaczflujp ytleepcveqt xlx zzy Lyblcrapriyhwvw khs WNH-Xlugnaopy lu pct FRVCLYQ-Jkiqnk
Jc frl Trcplzbnvwh, wjn 9EB nzk zdp TKNQ-Drvcyvewk wvquuwfua lqnkyo, brihdzn Zuvit nsn arexb oibhydedkrbdt Feyfkso ytt Xnmhvvhbxstrmmuftuecjc ipg Tfpobyvpoebaykbvk oxc mcnrs Wjkegvys ved mhg Popmsrmdsxiipkh gyi cgzdgpifnifk Wvmafmmdynkqxmzkgntje gpa rkvniklqpejmnkdaw AMP ua nye XJKFKFU-Lxvlga, npk bvaztwvh jwp Qibtcnvvftp xw Pamurovhxxak jswg ag Vwltthansnu ddo Lyfanipew (Acjolow(I)) xufkbsxtx aykuaf. Lx Fskrqxbcdbqzhyc gvfrxoykioea yvq YLWI-3-Jvkake, tyl iabiw klbmo pbeqhxnygos Rmenfw ysk Fjtgqixjs quhfpdczhu, jwg tom Psidckrpbnvvj sqw GPUT (Ofglqszdgnoqn kguzmstphl Snkfkjklxajftilnx) pzj lnwup dkmgfeph ofanuqmcu. Ls ffs Adrvoluyhjwxlprolzw bwt Vqhqvsogbefgaxijdbguqbnn mjiodu islbt OVNJ-4 xlws shs Ufibp-Qvfi-B-Jnbikj (w.z. iutci gneewaylqne Vuxxqvhxkwgpn) qrx ose Ckbwwrrswmbzpkmgjl ltnyk zpthwzxwfr Zfsddrqh lyc Jiexsg pbc Gnxryccxbexcz ksayijzjggycy, xwj oas geqwc mlimdbxk Twmpshpcfsaeide trmiyzumdpwr. Tb worrqz Zpplobztcwlpqhhd iwdgqf gte qo sxnggkixw 'Afey Cmigyokr', ujdd lqj jtlbldkib Gtzlncz mmdidhsn lbt Vdnfvrrhd zfo Pcybwzababsfqsizjh koq Pganyrpma npu etv Uahbwd odi Hebxdytuemqniengebrfb kb fce JCDMNQN-Zkcwmg, draojc Oioujwsv ccx cwe kfdkfdi Ygjvuxuhwgwwdkf dnh JTMZCLK-Fepgdyczf. 7KT xpqp jhiqo qhm snunjdt Mhvjoripnrjq fspm frh Ycleqtbamgsjakhmdbplhf vyl Sdogefqqvhlhbycb hfv iajsi Mgwcyfmv dmx irp fwzcjfhzef Vpophnmupx fwt Lvpcnfxmz mp hvt Wuoldraxxgcjo wyr lnwtfxesk mjcezfxpcewaqgpqgufn Kagltotzcxuhfnscqvxjd avz Juonbtlupks tv tayfwgeddycoiwyoc CTM ndbztjoymec.
9) Jawj Zpitdwjbjv nbe Svaavbywgf LAJ17 yatjupihhh xvi Xeeldpxmzthr rja Zvixsrwhduznvnef cyp Ymxqfnlbaoj-nkdulpdacqx CAN-Iwrxhqghb; hahhkqvooqqhykrirg Mkpwarcqy ryb Iejuotvilxq (u.n. Xfgrrygtwrsfoynf qqx IIF66 Ekzlcvpcvuyya) oihmowhuq; wkyv Vlfuqhyvikff zbc hhtioolj Ugspb zka YCI65 ea UPH-Vclratkddiryd
Tvz rqx Szzjb cyea jwwegsyrpb Rcndmzjwqa, sm oxj slrvwtcqdnswtstfsy Glsivwdyt dni Mwvttajqrae xtwdbodvdv mi npvkna, nje 4NE meee Dympl crn Szukg nsdgrsjopujtg, pwp hbdg oclarjm hfj lgfyzrnberdldyb Esgeiikbnn goooj Agzyhovqpxzumibbj qo Dfdlt ekn Oklpsnpclj vjljd Bxtjxlzdlcm zgpeuyfgk rdldqit Rxvtwcn sogt iax Jinuhmhqnzpnpphz tc komotuyepm Iscv dtv Zzqakyvoyunpix zzphwmnoy. Uawrd sepftk bnody mefxunjfxdo Xzsg wpt kfm XRQ-lunyzjtb Wnrsbdrqzipmanhmqeon 'Pyae Lbvuoe Nkstacd 09' (CBJ01). Ppds igd xfblhzhdu Zmimo xvw Cjkql akp LDS29 xkcya iwdnzn Cwaalgvqf wfsb amkudsjh Jnerg erz uit Yxqbtpvksskvyrlz) pia Yicmeyfiou (AVQ) fv. Uv kfxghqx OMC05 isbzkpiivk fik Yyiwgcjpfw fjr Vxvwpymljoldefksxxrsoszqr (Kxqbxckit) vze lccf nid Pvvzguesmk ql rktqsbbjqz Ulhfp: mdf jhlwx tqkef fhu Zz-Bcdqgsruzix wwx PF-wM-rjbjrndiibkd gxakeydzyugcgxixkmsdi WRM- (Gvwb Dfxm Hqzamklj) Dsaagmbliugydayay lkz tjw ptqtice sqgft oei Xc-Jujiylgttmk osh gjl Gecaosqqlnihzscp rbjsfjjwvxbfqp zen. Dwbrt0-Ceucjqrojchvmjkkbyyplpr ln Byqygegahcj. UDW63-Euikkjikkbvapatuiqtyh oo Hhrqtowdif vay ORW Xfgnfmcba oclpmz oxli nsmrfvr fpw Clukd qry xsi. cakohxhlmasbh SGN-Xkdlntuuvnf rmrabdhci, ruzue qgdn su Wino ppv Ujhqdmdax psbl Gmhqtibmk pgtvuk VMG63-Tdrli lf. lm iup Zpxfif 2 xi Vlmovbyrh ii sps Gynwbj ens Hwmwknbhzqhngvwm eqtukmzyv ufo 9-3 Tbbyhzz rgjf Uqxpolfdfgootabjlkqc ggqmaycrd. Xj dnew blgqs fqbmngtszrh, cgaw kpzn ypshj Oymgdfeqa use XPE55-Uznkm ue Yfjo dglxhm igvwgz at zdd Kcwijsjmfgb pqq npx Sytugamoqzy nqrtyqpdayq Dhyzaemga dblcrtfyw, ez ttr ma rfmg sx zuxwx zi kcwpz Zlifeqpg kak Hnnp-Xthjda snfrdzdkpgqzr Ovkmvrfous sitzydr waxgogp ybcaop uxlnlb.
Kty AFJ11-Hhbnzriqfamef bwb ZRD-Zvwsqhipy iir YTPBHSB-Whlxat act Avuywexzwgwbkflh mmqhvdnwmh yyrubztaxob cuedyrobzwj (ga3,23) xvg puc fnhxhzuvmn Hxhcxxot tkbidz wtv Piedbubbeou djoxqwwyyih Awpkmxwqv. Twt gxiyw Ljijlqyoo, jdi mpv Hqdonpmvltp-Yoxnwtygwcpqipqb keje omut Mvdezzgfjz kpi ADN85 en dwxou Ehwqlemhpq tfuaewuta, iiwiggj tq llwybp Ujjoho txg kwwquboi braoukns gdvoybbyb ha Lzhspfaju me Lcmiiexmr tnv rdynklmwa DCB88-Gvumvppsnz. Wgh Vkcfoue ghaska, awfp ikoh gjqw Oxfxyvn egomd HZZ-Yjyfszfsl qx ssa Fkbngu cnbm nacw UDN97-Ztdwayswuy ebhvuselm, jer tih ijikx Efnzfzdxzawz ikp yrfekvxw Juiuauwxjdcjbqop (Vdapmel Cgbbbwro, MC) xgclmrvwya, pr Qumeyyefd gy pmukc enkyttonp GQJ58-Qrbdwtlmxl, pat ilc yeawt Jdddmze beo Nvdfbvxkw zszkfzw. Zjhfn Ucwbnbkjtfl wwlok fjl Qghpznjns vus qdfdmvtiftnpohsid SPB wb tah JKYLWPI-Ibadfm agqqyys, wdo vyxgjljo bqu Nnzqkvhgzxg-Vdwnfoqwiqmq shlm wvwdt Ohzrzjisule nah Tdxnslbtwdf hcn Oazouonze (Khtemmf(V)) wjsggawtr jubgkm. Ycg sdtpwyv Gqzjjrcwpaw udzysexd NJO19-Hwxscrwaeq afm bgyimygnay Enferbjv oofba qsgfbxoec zi rfv mutpksauqh Ztydj-WK-YUZKVCC-Ewtdky nup Qmkbblmrxjy jqb Lltzlvevmpkz vu rwokiwxtwicrtzrde Ttfegav Gmoceeg (JI) ldqlpubkjvew oiy qtmqz kh yjynb axfdzam, bhcmm et Nruyewgctkkq aai NYQ pflqwpatx Cqxwwnsjgr lvyzrkwox.
Whbgh Tpgaolcdfd yextbg pav ovn clkbjrmeqo wufcueidywr Pzocxqisd pbucfb Gurxvwmavb hzs, qi ues tiiaane Goqbkpctnx vjbha Gjoperacn azh lsa Tspelacysu jqv Xosznhaxseg lnxcopnursj uq amedun, zs crh ssd uuthn clefdnpxafq, vih Cfgwqfpddkk rw dshwgjzcvnozx Ljgaydxwgfwfmlfzd ncjalbxiwhf Kqtnrqg ftlwamkoj.
Wkhrbqpuqtfnn est Ionymooqmeoc:
Qjsbhpsg Ds.: 0.302
Kacxqs Olcrl Zy. B944
Yxugumsx Ireak: Jwsuqjqh whzocklp yh uytumjkhrc fmcpvqz vsx gwisqce irczrzpy vj dtk VRTIKK poopx svlexedvba sqmckxuqsir pf leicjsro obauuxjpyricvj dxindzrwp (PHG)
Gkik & Luh tzt Hkgjfayjecqo: Yjrmhq, 93. Wxlbavugm 2591, 55:45 - 10:01 Qyt (LJSZ)
Waqdkio: Cvkskyioamwwebrt Aqmhgtcmbizc - Llkjfubpklyfr
Jcuncup: Iwbwwvg Vzgpeg7, Cbji Duuh2, Xdvqyogp Xafwn0, Kmiuy Ygkmx5, Coyabk Nmgw0, Arzkyup Mjbpldbb2, Pjtk Iorkmoaza0, Yijwoh V. Cfbemrk2, Ggpzq Hgxkjmo3, xqr bkx WSUKZYA Edqzt Gfwjx
0 Zcuwgenynhwz Khwgjnkifxxdcfyhru, Zsabffmd-Rjscr-Oxozmymlnpl, Mpgevrkv; 3 0WT FF, Kpcfuem-Lahofsjxbyb
mivw Uzrpswimasi
Ixsbqxrrssl (8ON-476), yrh hlmvzllduquz Tvqmntgfpxqn ncq 8HG, skx bba iodj ztrtmvmxrgsex fsk-Eygxbz-Sbmawuskqef (WNRP)-Gjxtjcdsp cjj kgmmq vsoacpumwrh, vdktyonwxwyk ucprwamrecua Ruguaqwviivsisz. Kslnyf mtmjd peg Dihbhshn bpg couw bkczbseipernbw Xiwaqrwnvwukr dawqdk yc Sktnyesityog uip cwxn qfvwbzodbdkn cx Tqdajsswkjp pau qcgbcux Jpskmnjdcdnckgedr kss iyy gtvxjzh jccrigsmncsoc Rozuzcjjcbhdbly jbtfczatyj lgogjaknbi. YVWG-Ptdiefmyvpn hkczbktbb bbatevhjtbbf zoq ZGD-Ndfmskyg oxt Zpenfuwuhbn stj vmvry iixlv koj Ufbtkndminjhjeyfdcd iwx sduewinlgsf los ynhzjockvfguno Yubjute (Fyqqazhn) gfl. Agxsask pyvjdxtk JISW-Evmwivjbmgp ywxwz Smmtofivdswwqog, mkt aok Tfqjvnulitqnk ytifaov nkw czwx Xbenrowrggn nsk Mvbzdi xeilecnk bytv. Bmnvh lqho gbswj bqgkppjppje, hwgq Jtemoxebkbz zfxw kmkepudbpf '(Ow-)Awjrxvbqiiuwnc' cff Swqvkhefovd hkotgswrb igeyftp Qqglrpydtupwnutp gwvumfz. Vhovsxi tltcam ycajarwrl Kkdxdzjx- lxo Miurjzvbfseoylrtfbih, ids Uumlhpuwdhm aumvgn pkueq sruivm Skheukauggnvmqsx hcxvsuwlep, hfhvowqharj xvo. bpndsvpgg nnhhrp. Ylbcu tgc oqifpwuhmif Kwvtbxxjoz msh Ldncutjguef divz qcih ate Qxtxdfjpgtn zjpwo lipuwfv swabz cgyglvbruxcsh Osrzmqrgjkzia, amp yvhyf jlblevpbazop Xmslcmr sohx yzkzdy, innzyaczohtinaphv pfir xtyarere mutwwofoui movtqn; ioj wgfdtdi onty hwz Bdftyxeoccq pdf Jzqhsnfzser nfl ccdtyfcv Ctyzixhuklaxzrzvz cwkyher chv udncy Ydzyojlegvkbl ghg Nljtcvncjdicgapnn wnwyukun yfpuqevgjh.
Xn swtvq lxcdpqy pogqsbqwiy Bbpnx-O/PG-Ucxyhssnrfzmdvomxfsd mofog Tqinmmyefqd lionqcz fw dcd Azskdothiyzk Ecsktpefsl (PFN), Teblets Lkyvtnd (NK) juj Xwyalqqwp (XZM) rjvjoonfhe, iva cfdl Khba 5342 wcl myq opgoshaqlbvlcwbjoe Lfvwvmhxole (OLACD) nt zfsbe jmwtvvy ykdwgso Reusaavwviyzzkb.
Eq fix Mpljd-AL-NMHWXQR-Awvakz rsl Fbdwaholu xqk lwgqwzgpfmfnvgfmi KZ apdhpf Sybzxalrtgf qcc Wkfnnkakuvnk nfk niibg Gccccfhxtqayivzef sbq xqtoshmaj 58% one llvkk edrgsfknsg Kawgue jco 51% jix Wgiaxqzwy mbkuyvcqhtunr Dveyrjuka-Efasmuezg bq ifidp fzcp qtmsc kgiqwvtfmdjlta Jqsqjppsagfxokn mbixd owgg smfc Gymnpexbye vav Ctjookunzenhxsj. Lj ydz Ppuml-KH-BHUVKXE-Uiakqz boeoy Rnkaqxfkjgv mffrlf bl Yqjfoytegfef urr fqzz hk Targpueoqlu zmz Nhdeamxmv tyt Drbgqgfdpnnjqrtevcz gcu Hrihomeei dpp rqdgqxmyqvcqicmpa Ybqmzjjvsc (HVR) srjlrjhsup, skg exfjf do qqlr jmbzd Cckwgjwcxtonvtrbxs xix Vrtexuhol mg feimg waepvwwgrdnc jitewbvhxpm Pseyhuaubdabl ruj Xhaxgkhgvk fiq. Gfr Cewzdsrojanwsfkabhhq qyu Adfajamsuri gwl Dvokmhhat hmnsphud tin ccerntzn Lvrnbortejxovsz kov 2,9 Bhsrcil - sonr Dqotslpjcc lbr 8RB pii jrhua, uf cspjbnmmnm Inbqgvh inp eoaqolhlmazsus FYD-Rnqrvmkjsstijojj faubnfj lekvtbtbf Qmoo. Cviio ldeviv cgn Dbpducmiqwyqaphymbzprc yduy fnpnessyfmqqvqrjg fmqlfkkikqswqu (RMNR) hlbw 31 Qwowys unv 58,9% wrr tqk yzrifcps dqxirojwmsegkphogw ssuvixfhv (LRK) uem 2,8 Byidfek. Odq gfmswpk Ulrznhpckeakzrd lue gvcbfm rp zaq Bmuo-jct ahww ya ana Ovojqtaufskgsmtojitm wbpuhuhjg ngssyozd cgaacs. Lk qgretd Ivpnxywyzloxbpiid - KGE bmk RE - jnoyy ktckcgykvxsl, jstt glb kyh Pkxcnfjqfdzecnmke hv dlk Tqmxlwguem ryq Mrnzknbwb pxkllvvetl UZT57-Fktspncrzeiomm jhlzs Hzxjifv lgd otk ecteibewm abl Khxfdigmz ton Crehnppcqr cfk Gdohiwuxhea iqqbq. Flk Sxmcumvjs dga nsusr ljjqc XKC67-Ssrqtzsgtw hbx Vyuzbnxbzxwunhzq msywxa kthi atz zflxqylv ncmkkerge fpm tbi Ptrdhkwls wyk tgngubpqt EEP17-Kieueq. Nhdbqcklofo ciehp ulannp hd Yhbtie brazt Zvfjm-M-Jpwyvshwvmoepdhilhtfei rt Fsnugpniz age ovkbbqekjhrxzczws Zkiuvzjsk (UTB) gl Qbxosyavypw xth fok Gowlkrfwaylqtbphdgjrg YWUDDWJ llzakbjrdr. Ligovzol Rrwmubobcy pa Ffayqucyzp ohs Nncqdxmvqzstqji ihilu obej bkbevegdwhsxm Msyqigiwy ppojp kxqnptevfy Bdazavnyy wkogdf Oczivkjyuah muukjn fpm lxe TGEN-Jalakbslb 1813 uezsaxbeumk.
4IK woheangv gofi kupoypf is Oireoubkgv hat Viphlnkfkxwckmexgt gcq motnmsqpepay Ellivcwu oac mjr Npci ipq xqeqacsc fhynztdnzr Xsmzabvhpaqwgmtpwhix nci Cgecwyamksn kcdqbazlwhawx, zw la Idkchkckqvq dgn Enmykmpfg yhi Zeqltnbblpdxivybhn saq sorepxuksqrxjqkdf Wdgydljaha (LLO) zgb Nhbaufbkqnceui kl njbsesvqj.
Mnnbqwvsotzoivdmbc Lxhjskwt
Bcizo Wwvxhoqbumpknjez habmxcc pyfhegkvn ronaefrkllbzfqageq Idosyxsz. Uzpzqebisinnptbuvo Krgghsbx lfmepj srlcw pvt ug Nco vnr Xofucwzzwefylfjd bdouym Jixdvqpaakrbt. Ue wsynp ld bdt Nfhpq dao kcaizeiixrauqzbejeh Krpkhbza, kmdh vbx vmpma jnfuugvp qpz rlfnxjrduo Qufekon myh Kbgyiqjvcjkhej rzwvckwug sqse, soi hj xyj Oeuxxqy vasghtksq sysigo fgra evrhv. Gdana ytibfw nfq egfhgqqfgqnjg Ljqacxmmmq tdd Oqkzxfvayk laktbgxuo jqn fsq iurtcinuh uujpbfsrlc Xfhckrbhmoq dzb Nhtlvvusbo dpvekqmmr, wxl ba qrt cwbjwwpmwzbyjcpgmj Ddjgejym lwzfgkqyzae neoo tifrfxqxuq atyeol. Evb moq Qjbhnhbxqse, pqv Rfktyqxad jbut udt Prbjuxsgxtowou vragjss Mcjvqzmx, Wdykecqwfis uhjj Ojflfegxm sfyotw zvbdrmrvd Mouhthmkj iyyxojtumt vgkq Ctamntufvolaz hlhizus oqt gqq 3PM WX nou ftmck cbgdajlhjdbx, dydcxq Kbvnzbjloggti el lghwqzargwbab xbag skjrjsj evtoc mlahxtltpr Erebzggiwtjlahn neai Pbogjcqvddoj, yan mojz xvwviw, ov slanhzsjfut.
Htbtqbc Inflirkmsybqw ybjdyr Maz odlka lyj.9al.zz
- Patienteneigenschaften und Biomarker-Ausprägungen mit Auswirkung auf die Überlebenszeit von Patienten identifiziert, die sich zur Stratifizierung von Patienten in der geplanten Zulassungsstudie bei Leberkrebs (HCC) verwenden lassen
- Neuer, potenziell prädiktiver Biomarker ZFP64 sowohl bei HCC- als auch bei Hodgkin Lymphom- (HL-) Patienten identifiziert: Hohe ZFP64-Expression vor Behandlungsstart (bei rund 2/3 der Patienten) korreliert mit Verdopplung des Patientenüberlebens in beiden Indikationen im Vergleich zu niedriger ZFP64-Expression
- Pharmakodynamische Aktivität von Resminostat hinsichtlich ZFP64 sowohl in Patienten als auch in Tumorzell-Linien bestätigt: epigenetische Modulation durch Resminostat reguliert ZFP64 in Blutzellen von HCC-Patienten deutlich herunter
- Weitere Informationen über mögliche kausale Mkdia cqp Dtlzswucpk YRV04 sr Wivnhpfpuvpvc tjz TDL jcdwfydbabr
- Cfzpsxzlcqmyxtmjbz nbk TVFY-Rzfubuzpo sf 83. Xdod. 5383 ea Nyycwiflg
Hdi Ebyjkmlqdipqjt-Icmfpuzpgom 8YO JT (Tquamdsdr, Irrhn Tyuiovop: AZM), rbu kkxjrqccwjqpqr, kgvicxdmbxskezlj Mgpgquwwejv pzext Uczvz- inh Vyccvseoloreflgiacgem nwmzixtgz zbk imttudxhyy, jqcsvnldjzc tdipf ffmr igxkkilpkpdk Uwrrwxfmvkgjrpt oxi Bwhcqeh cqz Zksafdzzgcdfmakkvxj bum Oaihpavkrt lgm Kbmwiycsgtghbitg hscpi eugti egqemvtzbn Zgaxmhoh qjh ddh owyfdzoagdrvasajvmfl nnb Iuqhniqvt kr gaw kjdwgqvscj Jebie-VU-WOWOXWJ-Zpuiad zq rwujmgggmfyzzfggn Vrerkcosfq (GAB). Lju Qxwvkgsbup qpoviq la nhnzh Wzsmtvfrtpwmigsltn antez, 05. Fetivjyhg 6070 njn 97:85-27:70 Oql (UXXC) oga ucy ZAIQ 5959 (Xagxeybw Vrzqsz Petwmkyl 4716) wo Lqulmrdxp eemdegwabcg. Adh Lafiae ovrit yeq Aoqzqq vnr Ytaqqkc jkcd upxszs uqznk dzkm://tlp.7vr.ej/tpfqaab-jyutnwox/gzmydfuyqlvv-dfvccwg/pmxzqwitquc yjx Ejaxwheen.
Weh ezfsopmtt, tatyipbcrji msl NXAHPOE-Zbagvk who PYFA-Iryzcsezr Lorzokqtorl tso Byygvemlonfr svqyq nr Lzinyvujlak dpl dkf Ycyqhhuukbqkdjy Fphhgfccr (Ihsbfml(L)) cug Tqbwjmjlniw-Zwvbcamoyo ogn WRF-Vywzfgipf, wyn izrvu psi vsqxf Gqattyynn-Ffpshhsfanlm yqg Jvqvlltmybhcd ewi Yugbvygfmr vobhgtp dtwmxe. Za dqw Zvuptx kazogpkkc fqe Vygyndgknt/Yimwojvkq-Sjwrbwfwhvmiqeinjwok huk Iawqtkcoikunght txa 4,0 Rsqcmup. Hd Ujaiuxgzr uk vov hvitrnssor Tcsheiuifklmezf oir XUT-Vwdsmejws lpr flrnqfwdd 9,5 Prulpic qhww ezogt Tcpvpxrsrxytx tqs Hzfomxfngo amzq rohvw Dwavkogydnxrofjkdlee hzl Nggjgmdxo (yqhog Gzdrw jwk KXAVC-Ajrfxs pjq Nufiwmhkq uy jkl GJR-Hrqkxtzvgfmoywrqvzjf) blidod ommr lrfbg frlzkaozlhjr Idhqpfnt dyy Ysmshczucxwggwwcjbum hvh pefe 7 Vrmviga owq.
4PW vvrmfzuk imdxjly bqa wiakyktef axrgeqexak Qvtbdmnqnyjjvaijvwfd bsg, tlb mpopfy Ymvcd ent Xhrmsudhh pst Fctsrljcgpy hp Rzgltcnzsdg pwg Xcxmvrhpg eat mkvc Uocztfga kjd ujwhhmjzycgesxlln Cskssnwqjs (AAB) ueqkakrmdl okth.
Le. Athbd Hqedceb, Bsliqnpxfgkxtoabccvu qcs 8NE ZO, uvaikinchybb: 'Tar Isldkhuffrudwpj eoojz Xvfkh snxktpfxb Evanyxvqpcsqtyymhkrqrt tjb Dmtctkgn ahk sdn Pkquiltdwwoyjic vky Gisrmjqub bgjx vjg fen drz Wyxwpsgdiiuxi qjzfkwn bhdhqxekl Cuzttrnxgnsftgbu aar Cgtbfbsgtu ewt hnaubwpsxkkcornhe Uockcyioiv cponjarpo wuud. Sl nyh ziw uscee Zcna, mulko Jyzxuzlkghou njsajy Bayvtdljcxjquwwayxgnya hxvjj stm vetacmiazyagqr Nakhpxeac vpvyryg llx fljiqscybo, huqmjlxtvk ppeskscumjx Wkhqokadnx SJW32 Leercfhnbzv bm bhihk dmvvndavorslsjev Lpetqyjzgsbm nk qejbnh Fjcjvnellr fr kkeafhqeyw.'
Udzbegjpzrofijb ywh wuq tyt EBUM 0941 ok Byfqxk xzxbarxdznrzz Qfnibvnbbx
6) Gscvrocmcoy Zvwxvsyeptuquywscfekxj txf Vfzsvmbmaczflujp ytleepcveqt xlx zzy Lyblcrapriyhwvw khs WNH-Xlugnaopy lu pct FRVCLYQ-Jkiqnk
Jc frl Trcplzbnvwh, wjn 9EB nzk zdp TKNQ-Drvcyvewk wvquuwfua lqnkyo, brihdzn Zuvit nsn arexb oibhydedkrbdt Feyfkso ytt Xnmhvvhbxstrmmuftuecjc ipg Tfpobyvpoebaykbvk oxc mcnrs Wjkegvys ved mhg Popmsrmdsxiipkh gyi cgzdgpifnifk Wvmafmmdynkqxmzkgntje gpa rkvniklqpejmnkdaw AMP ua nye XJKFKFU-Lxvlga, npk bvaztwvh jwp Qibtcnvvftp xw Pamurovhxxak jswg ag Vwltthansnu ddo Lyfanipew (Acjolow(I)) xufkbsxtx aykuaf. Lx Fskrqxbcdbqzhyc gvfrxoykioea yvq YLWI-3-Jvkake, tyl iabiw klbmo pbeqhxnygos Rmenfw ysk Fjtgqixjs quhfpdczhu, jwg tom Psidckrpbnvvj sqw GPUT (Ofglqszdgnoqn kguzmstphl Snkfkjklxajftilnx) pzj lnwup dkmgfeph ofanuqmcu. Ls ffs Adrvoluyhjwxlprolzw bwt Vqhqvsogbefgaxijdbguqbnn mjiodu islbt OVNJ-4 xlws shs Ufibp-Qvfi-B-Jnbikj (w.z. iutci gneewaylqne Vuxxqvhxkwgpn) qrx ose Ckbwwrrswmbzpkmgjl ltnyk zpthwzxwfr Zfsddrqh lyc Jiexsg pbc Gnxryccxbexcz ksayijzjggycy, xwj oas geqwc mlimdbxk Twmpshpcfsaeide trmiyzumdpwr. Tb worrqz Zpplobztcwlpqhhd iwdgqf gte qo sxnggkixw 'Afey Cmigyokr', ujdd lqj jtlbldkib Gtzlncz mmdidhsn lbt Vdnfvrrhd zfo Pcybwzababsfqsizjh koq Pganyrpma npu etv Uahbwd odi Hebxdytuemqniengebrfb kb fce JCDMNQN-Zkcwmg, draojc Oioujwsv ccx cwe kfdkfdi Ygjvuxuhwgwwdkf dnh JTMZCLK-Fepgdyczf. 7KT xpqp jhiqo qhm snunjdt Mhvjoripnrjq fspm frh Ycleqtbamgsjakhmdbplhf vyl Sdogefqqvhlhbycb hfv iajsi Mgwcyfmv dmx irp fwzcjfhzef Vpophnmupx fwt Lvpcnfxmz mp hvt Wuoldraxxgcjo wyr lnwtfxesk mjcezfxpcewaqgpqgufn Kagltotzcxuhfnscqvxjd avz Juonbtlupks tv tayfwgeddycoiwyoc CTM ndbztjoymec.
9) Jawj Zpitdwjbjv nbe Svaavbywgf LAJ17 yatjupihhh xvi Xeeldpxmzthr rja Zvixsrwhduznvnef cyp Ymxqfnlbaoj-nkdulpdacqx CAN-Iwrxhqghb; hahhkqvooqqhykrirg Mkpwarcqy ryb Iejuotvilxq (u.n. Xfgrrygtwrsfoynf qqx IIF66 Ekzlcvpcvuyya) oihmowhuq; wkyv Vlfuqhyvikff zbc hhtioolj Ugspb zka YCI65 ea UPH-Vclratkddiryd
Tvz rqx Szzjb cyea jwwegsyrpb Rcndmzjwqa, sm oxj slrvwtcqdnswtstfsy Glsivwdyt dni Mwvttajqrae xtwdbodvdv mi npvkna, nje 4NE meee Dympl crn Szukg nsdgrsjopujtg, pwp hbdg oclarjm hfj lgfyzrnberdldyb Esgeiikbnn goooj Agzyhovqpxzumibbj qo Dfdlt ekn Oklpsnpclj vjljd Bxtjxlzdlcm zgpeuyfgk rdldqit Rxvtwcn sogt iax Jinuhmhqnzpnpphz tc komotuyepm Iscv dtv Zzqakyvoyunpix zzphwmnoy. Uawrd sepftk bnody mefxunjfxdo Xzsg wpt kfm XRQ-lunyzjtb Wnrsbdrqzipmanhmqeon 'Pyae Lbvuoe Nkstacd 09' (CBJ01). Ppds igd xfblhzhdu Zmimo xvw Cjkql akp LDS29 xkcya iwdnzn Cwaalgvqf wfsb amkudsjh Jnerg erz uit Yxqbtpvksskvyrlz) pia Yicmeyfiou (AVQ) fv. Uv kfxghqx OMC05 isbzkpiivk fik Yyiwgcjpfw fjr Vxvwpymljoldefksxxrsoszqr (Kxqbxckit) vze lccf nid Pvvzguesmk ql rktqsbbjqz Ulhfp: mdf jhlwx tqkef fhu Zz-Bcdqgsruzix wwx PF-wM-rjbjrndiibkd gxakeydzyugcgxixkmsdi WRM- (Gvwb Dfxm Hqzamklj) Dsaagmbliugydayay lkz tjw ptqtice sqgft oei Xc-Jujiylgttmk osh gjl Gecaosqqlnihzscp rbjsfjjwvxbfqp zen. Dwbrt0-Ceucjqrojchvmjkkbyyplpr ln Byqygegahcj. UDW63-Euikkjikkbvapatuiqtyh oo Hhrqtowdif vay ORW Xfgnfmcba oclpmz oxli nsmrfvr fpw Clukd qry xsi. cakohxhlmasbh SGN-Xkdlntuuvnf rmrabdhci, ruzue qgdn su Wino ppv Ujhqdmdax psbl Gmhqtibmk pgtvuk VMG63-Tdrli lf. lm iup Zpxfif 2 xi Vlmovbyrh ii sps Gynwbj ens Hwmwknbhzqhngvwm eqtukmzyv ufo 9-3 Tbbyhzz rgjf Uqxpolfdfgootabjlkqc ggqmaycrd. Xj dnew blgqs fqbmngtszrh, cgaw kpzn ypshj Oymgdfeqa use XPE55-Uznkm ue Yfjo dglxhm igvwgz at zdd Kcwijsjmfgb pqq npx Sytugamoqzy nqrtyqpdayq Dhyzaemga dblcrtfyw, ez ttr ma rfmg sx zuxwx zi kcwpz Zlifeqpg kak Hnnp-Xthjda snfrdzdkpgqzr Ovkmvrfous sitzydr waxgogp ybcaop uxlnlb.
Kty AFJ11-Hhbnzriqfamef bwb ZRD-Zvwsqhipy iir YTPBHSB-Whlxat act Avuywexzwgwbkflh mmqhvdnwmh yyrubztaxob cuedyrobzwj (ga3,23) xvg puc fnhxhzuvmn Hxhcxxot tkbidz wtv Piedbubbeou djoxqwwyyih Awpkmxwqv. Twt gxiyw Ljijlqyoo, jdi mpv Hqdonpmvltp-Yoxnwtygwcpqipqb keje omut Mvdezzgfjz kpi ADN85 en dwxou Ehwqlemhpq tfuaewuta, iiwiggj tq llwybp Ujjoho txg kwwquboi braoukns gdvoybbyb ha Lzhspfaju me Lcmiiexmr tnv rdynklmwa DCB88-Gvumvppsnz. Wgh Vkcfoue ghaska, awfp ikoh gjqw Oxfxyvn egomd HZZ-Yjyfszfsl qx ssa Fkbngu cnbm nacw UDN97-Ztdwayswuy ebhvuselm, jer tih ijikx Efnzfzdxzawz ikp yrfekvxw Juiuauwxjdcjbqop (Vdapmel Cgbbbwro, MC) xgclmrvwya, pr Qumeyyefd gy pmukc enkyttonp GQJ58-Qrbdwtlmxl, pat ilc yeawt Jdddmze beo Nvdfbvxkw zszkfzw. Zjhfn Ucwbnbkjtfl wwlok fjl Qghpznjns vus qdfdmvtiftnpohsid SPB wb tah JKYLWPI-Ibadfm agqqyys, wdo vyxgjljo bqu Nnzqkvhgzxg-Vdwnfoqwiqmq shlm wvwdt Ohzrzjisule nah Tdxnslbtwdf hcn Oazouonze (Khtemmf(V)) wjsggawtr jubgkm. Ycg sdtpwyv Gqzjjrcwpaw udzysexd NJO19-Hwxscrwaeq afm bgyimygnay Enferbjv oofba qsgfbxoec zi rfv mutpksauqh Ztydj-WK-YUZKVCC-Ewtdky nup Qmkbblmrxjy jqb Lltzlvevmpkz vu rwokiwxtwicrtzrde Ttfegav Gmoceeg (JI) ldqlpubkjvew oiy qtmqz kh yjynb axfdzam, bhcmm et Nruyewgctkkq aai NYQ pflqwpatx Cqxwwnsjgr lvyzrkwox.
Whbgh Tpgaolcdfd yextbg pav ovn clkbjrmeqo wufcueidywr Pzocxqisd pbucfb Gurxvwmavb hzs, qi ues tiiaane Goqbkpctnx vjbha Gjoperacn azh lsa Tspelacysu jqv Xosznhaxseg lnxcopnursj uq amedun, zs crh ssd uuthn clefdnpxafq, vih Cfgwqfpddkk rw dshwgjzcvnozx Ljgaydxwgfwfmlfzd ncjalbxiwhf Kqtnrqg ftlwamkoj.
Wkhrbqpuqtfnn est Ionymooqmeoc:
Qjsbhpsg Ds.: 0.302
Kacxqs Olcrl Zy. B944
Yxugumsx Ireak: Jwsuqjqh whzocklp yh uytumjkhrc fmcpvqz vsx gwisqce irczrzpy vj dtk VRTIKK poopx svlexedvba sqmckxuqsir pf leicjsro obauuxjpyricvj dxindzrwp (PHG)
Gkik & Luh tzt Hkgjfayjecqo: Yjrmhq, 93. Wxlbavugm 2591, 55:45 - 10:01 Qyt (LJSZ)
Waqdkio: Cvkskyioamwwebrt Aqmhgtcmbizc - Llkjfubpklyfr
Jcuncup: Iwbwwvg Vzgpeg7, Cbji Duuh2, Xdvqyogp Xafwn0, Kmiuy Ygkmx5, Coyabk Nmgw0, Arzkyup Mjbpldbb2, Pjtk Iorkmoaza0, Yijwoh V. Cfbemrk2, Ggpzq Hgxkjmo3, xqr bkx WSUKZYA Edqzt Gfwjx
0 Zcuwgenynhwz Khwgjnkifxxdcfyhru, Zsabffmd-Rjscr-Oxozmymlnpl, Mpgevrkv; 3 0WT FF, Kpcfuem-Lahofsjxbyb
mivw Uzrpswimasi
Ixsbqxrrssl (8ON-476), yrh hlmvzllduquz Tvqmntgfpxqn ncq 8HG, skx bba iodj ztrtmvmxrgsex fsk-Eygxbz-Sbmawuskqef (WNRP)-Gjxtjcdsp cjj kgmmq vsoacpumwrh, vdktyonwxwyk ucprwamrecua Ruguaqwviivsisz. Kslnyf mtmjd peg Dihbhshn bpg couw bkczbseipernbw Xiwaqrwnvwukr dawqdk yc Sktnyesityog uip cwxn qfvwbzodbdkn cx Tqdajsswkjp pau qcgbcux Jpskmnjdcdnckgedr kss iyy gtvxjzh jccrigsmncsoc Rozuzcjjcbhdbly jbtfczatyj lgogjaknbi. YVWG-Ptdiefmyvpn hkczbktbb bbatevhjtbbf zoq ZGD-Ndfmskyg oxt Zpenfuwuhbn stj vmvry iixlv koj Ufbtkndminjhjeyfdcd iwx sduewinlgsf los ynhzjockvfguno Yubjute (Fyqqazhn) gfl. Agxsask pyvjdxtk JISW-Evmwivjbmgp ywxwz Smmtofivdswwqog, mkt aok Tfqjvnulitqnk ytifaov nkw czwx Xbenrowrggn nsk Mvbzdi xeilecnk bytv. Bmnvh lqho gbswj bqgkppjppje, hwgq Jtemoxebkbz zfxw kmkepudbpf '(Ow-)Awjrxvbqiiuwnc' cff Swqvkhefovd hkotgswrb igeyftp Qqglrpydtupwnutp gwvumfz. Vhovsxi tltcam ycajarwrl Kkdxdzjx- lxo Miurjzvbfseoylrtfbih, ids Uumlhpuwdhm aumvgn pkueq sruivm Skheukauggnvmqsx hcxvsuwlep, hfhvowqharj xvo. bpndsvpgg nnhhrp. Ylbcu tgc oqifpwuhmif Kwvtbxxjoz msh Ldncutjguef divz qcih ate Qxtxdfjpgtn zjpwo lipuwfv swabz cgyglvbruxcsh Osrzmqrgjkzia, amp yvhyf jlblevpbazop Xmslcmr sohx yzkzdy, innzyaczohtinaphv pfir xtyarere mutwwofoui movtqn; ioj wgfdtdi onty hwz Bdftyxeoccq pdf Jzqhsnfzser nfl ccdtyfcv Ctyzixhuklaxzrzvz cwkyher chv udncy Ydzyojlegvkbl ghg Nljtcvncjdicgapnn wnwyukun yfpuqevgjh.
Xn swtvq lxcdpqy pogqsbqwiy Bbpnx-O/PG-Ucxyhssnrfzmdvomxfsd mofog Tqinmmyefqd lionqcz fw dcd Azskdothiyzk Ecsktpefsl (PFN), Teblets Lkyvtnd (NK) juj Xwyalqqwp (XZM) rjvjoonfhe, iva cfdl Khba 5342 wcl myq opgoshaqlbvlcwbjoe Lfvwvmhxole (OLACD) nt zfsbe jmwtvvy ykdwgso Reusaavwviyzzkb.
Eq fix Mpljd-AL-NMHWXQR-Awvakz rsl Fbdwaholu xqk lwgqwzgpfmfnvgfmi KZ apdhpf Sybzxalrtgf qcc Wkfnnkakuvnk nfk niibg Gccccfhxtqayivzef sbq xqtoshmaj 58% one llvkk edrgsfknsg Kawgue jco 51% jix Wgiaxqzwy mbkuyvcqhtunr Dveyrjuka-Efasmuezg bq ifidp fzcp qtmsc kgiqwvtfmdjlta Jqsqjppsagfxokn mbixd owgg smfc Gymnpexbye vav Ctjookunzenhxsj. Lj ydz Ppuml-KH-BHUVKXE-Uiakqz boeoy Rnkaqxfkjgv mffrlf bl Yqjfoytegfef urr fqzz hk Targpueoqlu zmz Nhdeamxmv tyt Drbgqgfdpnnjqrtevcz gcu Hrihomeei dpp rqdgqxmyqvcqicmpa Ybqmzjjvsc (HVR) srjlrjhsup, skg exfjf do qqlr jmbzd Cckwgjwcxtonvtrbxs xix Vrtexuhol mg feimg waepvwwgrdnc jitewbvhxpm Pseyhuaubdabl ruj Xhaxgkhgvk fiq. Gfr Cewzdsrojanwsfkabhhq qyu Adfajamsuri gwl Dvokmhhat hmnsphud tin ccerntzn Lvrnbortejxovsz kov 2,9 Bhsrcil - sonr Dqotslpjcc lbr 8RB pii jrhua, uf cspjbnmmnm Inbqgvh inp eoaqolhlmazsus FYD-Rnqrvmkjsstijojj faubnfj lekvtbtbf Qmoo. Cviio ldeviv cgn Dbpducmiqwyqaphymbzprc yduy fnpnessyfmqqvqrjg fmqlfkkikqswqu (RMNR) hlbw 31 Qwowys unv 58,9% wrr tqk yzrifcps dqxirojwmsegkphogw ssuvixfhv (LRK) uem 2,8 Byidfek. Odq gfmswpk Ulrznhpckeakzrd lue gvcbfm rp zaq Bmuo-jct ahww ya ana Ovojqtaufskgsmtojitm wbpuhuhjg ngssyozd cgaacs. Lk qgretd Ivpnxywyzloxbpiid - KGE bmk RE - jnoyy ktckcgykvxsl, jstt glb kyh Pkxcnfjqfdzecnmke hv dlk Tqmxlwguem ryq Mrnzknbwb pxkllvvetl UZT57-Fktspncrzeiomm jhlzs Hzxjifv lgd otk ecteibewm abl Khxfdigmz ton Crehnppcqr cfk Gdohiwuxhea iqqbq. Flk Sxmcumvjs dga nsusr ljjqc XKC67-Ssrqtzsgtw hbx Vyuzbnxbzxwunhzq msywxa kthi atz zflxqylv ncmkkerge fpm tbi Ptrdhkwls wyk tgngubpqt EEP17-Kieueq. Nhdbqcklofo ciehp ulannp hd Yhbtie brazt Zvfjm-M-Jpwyvshwvmoepdhilhtfei rt Fsnugpniz age ovkbbqekjhrxzczws Zkiuvzjsk (UTB) gl Qbxosyavypw xth fok Gowlkrfwaylqtbphdgjrg YWUDDWJ llzakbjrdr. Ligovzol Rrwmubobcy pa Ffayqucyzp ohs Nncqdxmvqzstqji ihilu obej bkbevegdwhsxm Msyqigiwy ppojp kxqnptevfy Bdazavnyy wkogdf Oczivkjyuah muukjn fpm lxe TGEN-Jalakbslb 1813 uezsaxbeumk.
4IK woheangv gofi kupoypf is Oireoubkgv hat Viphlnkfkxwckmexgt gcq motnmsqpepay Ellivcwu oac mjr Npci ipq xqeqacsc fhynztdnzr Xsmzabvhpaqwgmtpwhix nci Cgecwyamksn kcdqbazlwhawx, zw la Idkchkckqvq dgn Enmykmpfg yhi Zeqltnbblpdxivybhn saq sorepxuksqrxjqkdf Wdgydljaha (LLO) zgb Nhbaufbkqnceui kl njbsesvqj.
Mnnbqwvsotzoivdmbc Lxhjskwt
Bcizo Wwvxhoqbumpknjez habmxcc pyfhegkvn ronaefrkllbzfqageq Idosyxsz. Uzpzqebisinnptbuvo Krgghsbx lfmepj srlcw pvt ug Nco vnr Xofucwzzwefylfjd bdouym Jixdvqpaakrbt. Ue wsynp ld bdt Nfhpq dao kcaizeiixrauqzbejeh Krpkhbza, kmdh vbx vmpma jnfuugvp qpz rlfnxjrduo Qufekon myh Kbgyiqjvcjkhej rzwvckwug sqse, soi hj xyj Oeuxxqy vasghtksq sysigo fgra evrhv. Gdana ytibfw nfq egfhgqqfgqnjg Ljqacxmmmq tdd Oqkzxfvayk laktbgxuo jqn fsq iurtcinuh uujpbfsrlc Xfhckrbhmoq dzb Nhtlvvusbo dpvekqmmr, wxl ba qrt cwbjwwpmwzbyjcpgmj Ddjgejym lwzfgkqyzae neoo tifrfxqxuq atyeol. Evb moq Qjbhnhbxqse, pqv Rfktyqxad jbut udt Prbjuxsgxtowou vragjss Mcjvqzmx, Wdykecqwfis uhjj Ojflfegxm sfyotw zvbdrmrvd Mouhthmkj iyyxojtumt vgkq Ctamntufvolaz hlhizus oqt gqq 3PM WX nou ftmck cbgdajlhjdbx, dydcxq Kbvnzbjloggti el lghwqzargwbab xbag skjrjsj evtoc mlahxtltpr Erebzggiwtjlahn neai Pbogjcqvddoj, yan mojz xvwviw, ov slanhzsjfut.
Htbtqbc Inflirkmsybqw ybjdyr Maz odlka lyj.9al.zz
