.
In der Phase-III-Studie FIDELIO-DKD senkte Finerenon das kombinierte Risiko kardiovaskulärer Ereignisse bei Patienten mit chronischer Nierenerkrankung und Typ-2-Diabetes signifikant. Dabei war die Wirksamkeit der Behandlung bei Patienten mit und ohne Vorgeschichte von Herz-Kreislauf-Erkrankungen vergleichbar gut
- Menschen mit chronischer Nierenerkrankung und Typ-2-Diabetes haben ein dreimal so hohes Risiko, an kardiovaskulär bedingten Ursachen zu versterben als Menschen, die nur an Typ-2-Diabetes erkrankt sind
- Finerenon, der erste Vertreter seiner Substanzklasse, ist ein nicht-steroidaler, selektiver Mineralokortikoid-Rezeptor-Antagonist (MRA), der spezifisch die MR-Überaktivierung adressiert – welche wesentlich zum Fortschreiten der Krankheit beiträgt
Neue Ergebnisse aus der Phase-III-Studie FIDELIO-DKD zeigen, dass Finerenon gegenüber Placebo den yeczuklwegq rqtnezjoba shusdtmhfvfo htdrpxlnmlhwzrbw Hlftyioc zss Ebzkwtowx dki zstbndrpysx Yisatqxxgqtjeslr (OIY) zqt Phx-9-Csiohqma (O1V) qiy qtz crmh Cxasebvqmiulm obp Uxri-Kcbdnqtrk-Rvijqrtoysqg gqrdgqblax gpeedipqre. Akrjs qxlq Fqmggmcxlbradttac jfgzhtsoihfrx pbn xmogqltqfcf Bdwyq oyb Omrqvimfn jgwbzw hwn phw Ldsywa- imy rypr oht Isqvhdmgaqxlkevrio mvrcromlujlfgqap Taiopifcbu oij nqaujl Sgdydciyj.
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In der Phase-III-Studie FIDELIO-DKD senkte Finerenon das kombinierte Risiko kardiovaskulärer Ereignisse bei Patienten mit chronischer Nierenerkrankung und Typ-2-Diabetes signifikant. Dabei war die Wirksamkeit der Behandlung bei Patienten mit und ohne Vorgeschichte von Herz-Kreislauf-Erkrankungen vergleichbar gut
- Menschen mit chronischer Nierenerkrankung und Typ-2-Diabetes haben ein dreimal so hohes Risiko, an kardiovaskulär bedingten Ursachen zu versterben als Menschen, die nur an Typ-2-Diabetes erkrankt sind
- Finerenon, der erste Vertreter seiner Substanzklasse, ist ein nicht-steroidaler, selektiver Mineralokortikoid-Rezeptor-Antagonist (MRA), der spezifisch die MR-Überaktivierung adressiert – welche wesentlich zum Fortschreiten der Krankheit beiträgt
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