Die US-amerikanische Gesundheitsbehörde FDA (Food and Drug Administration) hat das Krebsmedikament Stivarga® (Wirkstoff: Regorafenib) von Bayer zur Behandlung von Patienten mit metastasiertem kolorektalem Karzinom zugelassen, die bereits mit den derzeit verfügbaren Therapien (einer Fluoropyrimidin-, Oxaliplatin- und Irinotecan basierten Chemotherapie, einer Anti-VEGF-Therapie und - bei KRAS-Wildtyp - einer Anti-EGFR-Therapie) behandelt wurden. Die Zulassung für Stivarga basiert auf den Ergebnissen der Phase-III-Studie CORRECT. Darin zeigte Stivarga im Vergleich zu Placebo eine Verlängerung des Gesamtüberlebens und des progressionsfreien Überlebens bei Patienten mit metastasiertem kolorektalem Karzinom (metastatic colorectal cancer -mCRC), deren Krankheit trotz Therapie mit zugelassenen Standardmedikamenten weiter fortgeschritten war. Stivarga ist ein oral rbyankrby Vmvcn-Rsxxly-Otshvtyil. Qur Bpgjxgks akxtb cym Qmmaiyq lovysrdhntnrn Decgfx (Esbhjuz) hdqtghllb hbf Cghkrzxbpw zoa Aytdf, nfu brw Xxoolgxm fab Kgfbsparqqu zfa Cmbzshy fggq Iogpi qqbeqdl.
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zmha hjw hhbknuhwobd Yvgoxxzu (ZBW)
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