Die messbare Resterkrankung (MRD) ist eine wichtige Größe, um den Therapieerfolg bei einer Akuten myeloischen Leukämie (AML) bewerten und die weitere Behandlung patientenindividuell anpassen zu können. Eine entsprechende Diagnostik ist derzeit noch nicht flächendeckend verfügbar. Ein internationales Forscherteam unter Leitung von Wissenschaftlerinnen und Wissenschaftlern des Universitätsklinikums Carl Gustav Carus Dresden und am Nationalen Centrum für Tumorerkrankungen Dresden (NCT/UCC) hat nun ein schnelles, einfach umzusetzendes Verfahren für die MRD-Messung mittels Durchflusszytometrie entwickelt und an Proben von 246 AML-Erkrankten überprüft. Das Verfahren könnte die MRD-Diagnostik künftig für deutlich mehr Patientinnen und Patienten verfügbar machen und die standortübergreifende Vergleichbarkeit der Messergebnisse verbessern.
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