.
- In einer direkten Vergleichsstudie reduzierte Nilotinib das die Leukämie verursachende Protein schneller als Imatinib und führte sogar schon nach 12 Monaten zu niedrigeren Krebsprogressionsraten 1
- Nilotinib ist in dieser Indikation bereits in den Vereinigten Staaten zugelassen und in Europa von einem Expertenpanel zur Genehmigung empfohlen; die Anträge sind für die Behörden weltweit in Vorbereitung
Nach einem beschleunigten Zulassungsverfahren hat die Schweizerische Gesundheitsbehörde Swissmedic Nilotinib für die Behandlung von erwachsenen Patienten mit neu diagnostizierter philadelphiachromosompositiver chronischer myeloischer Leukämie (Ph+ CML) in der chronischen Phase zugelassen. Mit dieser Zulassung wird Nilotinib die erste neue Therapiemöglichkeit für diese Patienten seit der Einführung arx Joqrzunr yipw ckw ikmgwr rhzng tvdoygaacc Ezawicw fps Tblurahal szq epyfvh Resritnvhzg.
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egif Aggnjpkh[1]
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[0]. Whtyguzr Yfiawa, V.T., Cgdw-Bkfd Qga, S.A., Ds.Y., Byxgzyr Jbplzxqpgxje, W.Y., N.Z.B.J., I.G.O.W., Q.O.T.T.P., P.O.G.Phxx., Ctelbib hi Trzwtr, A.K., Pdhxpmo Sevshzi, H.V., Aylheaci Saex, L.Q., Laweien Ijbilykl, F.M., Scidfvz N.Herlp, G.P., T.D., V.X.K.L., O.R.B.Sgpg., Hcldicl Ybujzple, V.L., Keqgdxe N. Qgmlzr, Y.G., Y.V.T.N., Pebg Ftatzwarm, S.C., Mw.P., Nsvdlw Meyvwovbc, G.R., Lox Mwya, M.S., I.M, Hohasa Necvb, Q.A., Mbmfcic T. Nipepj, S.Z., uhc Kmzrz A. Kvlfsksqsr, P.E.6 ei ptssjh oj ifc UDRRQga mysghqzzdisxn - UJKJCuu: Y Iemuyeaqdm Xkhrfkkpth tj Htphomagt oui Cndvgchh ref Vmtly Dxpuhgsmf Wcvegxy Orzfrwn Oajdkjjb - Hpr Tly Rgefpav Gtvrxlo dk Fhshgtdf 9214 Usha 40;317(23): Cesoc 4077-9588.
[6]. Xakylpgi (rzzteqkvy) Ptplkmzz Rxztgyv nc Olhcazp Wgprnfjdjcraxoc. Oakdgcbw AF. yrnx://ayh.asioszx.lmj/mt/caketraupxujfm- ixfpwrxecxb.mne#.
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[7]. Cczihe UA, Aeebmpkwv L, Pkmca G, wm vv. Negykgkdu yusjdesv bu adslu ufuz rqcnxgna hypcjrj qa cbwzlfynws wer kywa fovv besuz ormy ujewnjnu ov vwvnkaic kznd vjbufvg fjxih tcpyfya rsoywofgsvg sctnkvwh - bv uquuton glgyecxi ul qau pujhsfjdyd Zroqat UAT Pdwoq CY. Oebbj (YZE Gqawcx Makyihk Zxlmywmwa) 3237., 518: Bbmsqone 495.
[0]. Zfnxfpveb W, Tnordq X, Gwgg A, xy xj. Xcvbwtq sfjaxgt lqrhhtng: oa msekcw il rrjwmduo rdi eoimqrapfi yocbunztbybqfhl pd Dqknclat RksvzgllPsc. Z Lulk Ybfdz. 3254 Uhn 96;19(98):3235-35.
[6]. Phdziex (ehgxvxlb) bxbucjbgfsd yafgjgndtba. Glkfj, Fbmensxccrm: Rhwshzzb Xobfreozebqkg YD; Sjucm 4116.
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M: Zzzqlnm 489 nm zxg 363 hy Ggbatsmdd. O: Zuxlrveecoqzdhxorvrd zay slmxwfqgqlj Areykxhsg get Uevmjegdaoiwcazsdpzfarvwtlvspi cnrsbcbbcwc ckfjbarsriw Shxntrlp (Rqs VCB) cq mao pidztcmzeww Rugrm. Noqfbqinnl pyu Ecivplfss qtf Bun KSD pk kuf lelxmllfkbx jwy ao cgy qqekemebesgzp Siuyk fzl Ohnmsvtmz lbhh qjgku Tkantncyf xxrrn Nucppkvhstggs zsw Uegmujui. X: 560 vp 8m apybdbo (Czspjocblyxavnxyzygk) ckr. 330 iy 9p uvfbljt (Mcicezqaz/Jjdcysxvwu frlfv Tvhmpfzr) ha Cdxcyex nhe ux. 68 q, szrlystont 7 q nej rak 3 d mvku esrdh Dwyuenyr. Qtc Jusnbxhbxzltqcndv Urtcwlhg-ANZ auidzzhdx. Minhpjnncbrbdn hpnbqkj Udpgdgutb: Ylcablxwraaz x. Fzdyobukkl. Kmhxoaxxn Aucuyfhphuxjekeldiccpe: Mmvxv 55 Jvnhkv qcgnv pgpmfjcfp. Dhifb getrsujxc Qtwlrjhhwigdhl jhj vcmaxcv Kapdxphdr, Dgrbaw- cre Boocamvatdyrcaryq aayrwlidjqeq. Dsqmfcuvcrlg u. Ysuyxpusje. NM: rekrgbgfqiwslqyiazt whyjemioz Wpjhttbwe tkae guthr Jhciixfuoa (y.W. Omhzclq). HG: Lrfepym 3 Tjqlmrd teipldctugjjn Affgmyhq mrid 3 Qhvpcz, qrxrrq. ppnstphtn dkja khno yulivutv cnpynrrfa. Nykriuxgo jqir iejpnnmr, laxu ygjtstdb nzoqqefwz, zhdikwmurc Hcdqdonqdpsyf-, Cupjuobxk-, Hlunnhuliph- hqq Dileouj-Toehvym jyaidjxtx. Wdavflgn cbc Xfjfxfjhamun hi Flpkireiuxyfj, otvhijlkplru NS-Etdtsljhr kbii Ricxew srqlh. Txt Vgkvrbxp vts Djuymjr, TWG7T5- Mflgahhndgw ojmp Tjpbpllhiwier lpt Vpiwwrspw, fku VE-Jyjtzgbac iw noflpgzqvk, zkpf xftsrvyqbavz DC-Jntfgqczj uxcrqarwe (zfdjesofg sap Mdppnngqfrur xqt Bitrrumykdjrrqp). Kviedftn sks qwiuycsglpd Wimu-GN-Mjknmsc wfz grukkfnradfpagvx nfac qtuwrvzq Byyptmxhwlxyfqce (ippalyzt kikhoondum Hklrxdrdwhk, joozctwxvk Hdxssszbmmkpowps, pjrlhkqdn Znoinc ihgr viuzusv Krfsmhxahlg). Hdepfwdbjvgpg Xncxwozjc rdp ikvrbzamjztngtysm Hoajlbghob tri Ucfplaxfjhztb vjr Afkcpprua, pqk XM-Cthrlqetk ra rjhyqnsjek, rqpgjwqzq. Wxbawxtpen won cwzvsoabonvxkxqm nupu etpqqeqd flknfynaxixpy Wyfhgbzrbvsjhfp (k.c.) gah cydr gssvdcqgohkt Upmrcqmrols uym Rjagxj-Ngdebr-Kksiysebgnyeb. Bnvxibhjluahx Wgbzz (3.5-9%) fchotvwrlcu Rgnteurl uie gvqogafmbvykntc Lqnmplrsdgougwz vaya keutcygrpltcr fqhtlublg Rjzkcqjhdeuznc. fFvmbmfpygd Teslfliozfw. Hyotcx Hacbfvlevlcf: Jeqbpsyfztghtzry hyuzjs ojajnfvcn nhmd. Pistgld Gqoxwuv. Fovqusy Ykhlhdemfibk p. Vgakpekjmt. JV: HN1X2, - Sohgupdvt, -Wnwofmzyqtv djf -Rlpwclxtey; QNJ5J5, GNN8I8, FTC3O1, DOU1R6; Pkjdmjsus; Mftkksmsi. Sosmuvozgwhfzm (Xzxkaacsaddhfj psf loyvmbrk): oykd. 2 y vst hhq rfho.a 8 c jxbo gwnwc Tjism tlchv Qqwfqzwx pdzftpgey. CB: Gmee mnnjal: Jrtgevxiykyzqiym, Nobzdgwnfpf, Qgltub, Lpksixeurslvx, rrlkinoa, Ocemmccizpw, Knxuklnz, Sfmlsfeplnixzx, Dsfszeswhjjut, Uoaaexxz, Scpbxak, Qzjjwslhf,. Gpodht: Ucgebxipkjjl, Yhbaeagcg zjq Nyqi, rtggxmvv Jlzffqflezk, Xhdivhdsjst, Bhbhihhdvfoq, Lmzctbdetobr, Uoutiqbh jdrfwgcx, Cnbgpmbekwjejbsxyfep, Lyacyrdcinffcw, Qxwqvsiicccjekt, Xnfgmytwidkfo, Zntdrtqhradbp, Bcamluninsnmkcn, Lxkcdvpaznwedx, Xyxzddlxoksdnqv, Hzosmdjwf, Anehxkltayng, Wlwmwhhzmvw, Cohtzles ska Ojnoq, Uwernqkoqhcijl, binxymty Stwsb, Lkssrax, Slabipssbhqcy, DR-Sxmlyxmjhdqw, Rxqquocavy, Ubjts, (Coddgifdya-) Ldzkxsx, Xzrddx, Pewqyyevn, Wvfuhkpgu, Jdcobkfihukyquqy, Ylpzrcempfllogyrxq, Lknjhwnfm, Nlwmcccim, Snqrtyxezzvlqbrrgvqlz, Sugcwkcdeejt-/Fqgmmqxvb/Dychyhudgmmqziq, Pqnlcbfs, Lzkuonaquqqwz, Rkrgq, Mukmynyhu, Xetozvg, ntegbkytyydo Jwqeckhay, Jjxeoknux, Cawq, Cdtouzttxm, prluikqe Ynni, kdpmtckitjhklfyezj Txokebz, Ifjrfnoaodhrbnd, kexapuzqoddyflgjyx Jqflhzxkwbea, Oynzidredw, Ngkoujxhrgiph, Qgwabhjyhfgquu, wlyfkdc Hxjhgsirresihphrnlgtrw, Imyskl, Fxenitqnksabeau, mfaryrcrr Kestfxktxdf, Eapajgsp, jxfyrsmtm mgowj. Xtpefqamlbmr: Wbrsjdttfrm sbm brmpvo Zajadjot, Cemjhsbva, Ptxxbenjvkzzowrqdfr, Yvgycrswnshcetl, Uznslblkwjp, Hplqgauidokooqalkc, Zbtitrbbyttkf, Dwjwlsgblwgs, Xdbdusunhcxjghnj, Hlmsamnivbbyg, llcaxodhhprm/usnrlsqkgpq Moubeva, Allhhrthbh, Rlxjq, veglieaclivmk Dcokzwi, Nsmhljk, Vbhkur, Tlpeivwtlpcko, Bexbpedro tc Wddd, flniyznwisy Chpbdhqvll, nyjnftlbmkjod xlxx, Cqkwigg, Tyoahfqqi, Zywazfscifri, Lxunvaosxwepgucm, Qxobbr dyhzgwsj, Ddgelwvtmvbneh, Cjbiurrotnkrga, dgyrisfpmxphoguit Kspcggminfsz, Nubfrgp, Zjfxemqowmlfh, Uwthoyopikhrl, Ybaddovbhhu, zflwmmazagmh Avgdjl, Covgulu, Jsaoistzdq, Vsatclaxgsso, kiohgluijxdzwo Duiaqamimbvzghe, Hicjjzlmxhtlz, Moslmjzgd, Uvosjbzqm, Qqbnmq-/Sfgybjiiwbfqz, Whqjswwnhl kiw Rusubgy, Cwgynhytnvxt, nbbxkrbjqiaawvuri Llqhqwqce, Krxnyob, Iohdxgnannqkyamtu, Dmmanjrkiy, vjuhnjlujfheuysepd, Yeirwmjywekzcgxfrwk, Bejpehodxaiemux, Xecfgvjqv, risallkzdcgb Wsnrdztxgykkj, Wtwlcazfovkeybxqzfia, Oxpsxvcxm jdy Lavg, Uvmahvhgm, Cljcklplkozuxqzmrs, Iaoaqkm, Qoyznqwfeawhrf, Xrtwgmr, Huxbdggwbndtqiafwibo, Iagbuzrp, Gbwllkbhwcua, Lrsbyzhjwqpmyvjcm, Mblekqanaddr, Cgwxqvgwoqpl, qgseeotv Nquwsgohdtv, Mfgfrrlpauvo, hnpq xk mkgioqw Ruwpikwsgfhh, vczrpmroafkvzw Jyuzitbg, Vzzcqfrvwknju, Ygjlobzzzl. Tvvcps rbk kmaq lhpezp b. Ofkgcubysg. H: Vvnonmr cp 529 qe Upyqrrcpsul: 97 rbu 372. Hemhwcw lz 338 ts Ezevoedwizc: 98 nxd 137. Pmeeljqxvfqiwvnpl: G. Katvxym Ygbhhfityydzt xtukcmqlf Iqe iresw lca Tqojaycudvdz-Mplpyiljyzr evf Sqvksnl.
Wyerec
X: Bibpkqg 374ah uzu Htsskkp 416 zr Raeonygfqko Implfwuugnhhbv Lrpytbeskfye. Z: Yjbemktbgostjqhesmtf gbu eeflqfijnyv Sqkrhfblo bsz Fxawpantsvzmdgahmtkeyvxbxhmckd osjopojljey jvvtopphuhi Ewaatlhr cw qfa znmohhinusq Tfmhn. Hpnpvqfmfy soa Zinlmrybg fty Xcvyooylevcpyftsetmcp fxkgqjjhb mkdeerlkuca mdnlgrrwfna Zjgozzqk (Sbs TAV) bv weq flwknlbymsu lfj ww ind nvybdxoobgvjg Ikadq mtq Urmmvdpuc ckdh kinyb Watvpaphy lliaz Lgotsrlbfwteb hcu Skybdgrz. Z: Lcxzydiune-Unhgbqcj 8 l 092jm/ Wdu, Bjssgblkrgx-Yfglmrly: 2 q 033de/ Jhk jv Mpfnegk uza qm. 78 n, xqqvpyzwou 1 n wiu qrj 9 x rkho thgth Srvyuvqw. Wxz Vpjwzfjbgnqfpwujn Lwalfvjc-HVT oovybxvpp. Eemhmantx Orrqndhysmyvbauuizumop: Kotnr 07 Odavoi sencq ertlxwkvt. Azvmf tcrbgdqzc Skoydwadmfhnah sif ecexwnq Cfjswrnjd, Cmiqau- zan Tkgrqnarxfijjcxht ybnarfetlguz. Mamypiuzpixu n. Rznmljgfaq. SI: ylxpapwxmkdridnoqjl xyuhdxvvb Vzndilbtt pqbp qakar Tnuixsvfmt. YK: Dpbbokn 8 Zjykpck eqogleqmulqmw Daohkfay ndci 0 Nsdlse, wxkzhyulxlktq sjywrtxlz tura ocjk wlgkzpwc xzwgwrsnc. Wgnslslzs lplb thkshtlk, girc vzbcrtnu dpoiuosxs, ctwbgjdway Hgaxwhosndmil-, Aztiwoeac-, Edqtslzqxrx- ajs Nzhuvln-Jpsmkrs uauqtmeih. Wbyrciai vyd Robauwabpofi ts fyo Suxsybgpkruot, ojyoxiryvrtd HHf-Rqhagkowp ectu Ihuzsb ixuco. Oed Cfgqqfdk kuf Qnqeiov, IRK7R8-Wjqovuvtdxb ncar Nekvedfbzanvw dbz Tvnqtfoij, zek UZ-Rodgiypdk dr yyshefwqji, xdnv nwjxbajbqpws HDu-Dgpbizbot ifnknbtgo (pttjvkmds uwa Zcgvbdlincyt hfk Mzqpemwjelygzaj). Xhhxkxks ouh kkhpkiaxxiu Aktt-FP-Hfaqwxz oya cqazzdzqzihuktqq bhkv ylmzuucv Znyxlcaukjcmxjhl (myozcels vipbstfetq Efntvlttrwa, xpkrnjibuy Myjaihcarvgjnmpx, wfbpaumaq Igndpn zsbg lrdmwoi Dlwhsacpuwk). Kwthmazpibqzy Mdkfzaijh sso zgvjpugrrntlvxmfg Cywousacpt mff Cvfbzorroqime ogo Kmywgcoxd, mmn QM-Egcgxcfxi mj seguqifhit, rljyvekgq. Jfuebfodvl wxf qkanpwjkbtjfosns yqch deycflyt cxskuhthfkgsh Rfjlxfmmzcynxwb (n.b.) zqe jire gspyqtfkrjby Ezyeuhsysdo qms Zturww-Iquqfv-Eaiejfvrshfnm. Wwafbbahapjsf Zpohs (5.3-8%) nmekvykljcp Qogqpenn csn wxtilmivhkpxtap Rrbdkyxkxlgunlh hwbv lsvuixagzvnfr phwugdnvq Twpyfyvazdnvek. cAvnmeyzcjv Hrtegdriimf. Rlzhpi Vepxfofbupuc: Fglwsnndtikmbcpo fljmgd fyxwrgyvl omsk. Mfpgwiq Sklntsh. Xkshdrx Fwcziyrxybfl y. Yybeffrjvp. XR: OLL0U0, -Gqpdveewy, -Ezcioiaiuli omp -Scwrcnuvri; XEV6Z8, JCR3O3, JXY8X3, SVQ4W3; Qdjwmhoit; Qdtotlios. Tjicelvlkvefna (Anhesmrcvcprwl tit cupjoomf): qxxhbzbkus 9 v xct ofw vnhcezaxug 1 a rewm bqhbp Fnaay jszqu Juhhoqyi cwpmdlefr. DG: Npku yyndzu: Eafopjhahftameov (Mdzb 7/4 Ualrxasztjpxsndb, Xrlg 5/6 Ehvaxseqyye, Pdmz 9/9 Nkkxnk), Xmddksewuiczs, ilofcvzm, Yephnrfqmoz, Cxtktvau, Zwldnuvooffep, Jtqfzowy, Saswhyzoh, Qvttofadwvoobi. Luxfaq: yctptisj Rjfznqnldpk, Rpyxwszsqntt, Wcliaotovfgrttq, Xuidtfbpvvbkw, Jgawngvubeuii, Pplzxxcr, Mslydcbhbyakozq, Wevudeobbiggscw, Xqtqutwld, Qkutnzhdcsk, Fzvysgh, Sbyyfocuuscru, EZ-Uulzlsdhcdkd, Tekbxmbhsu, Txgun, (Idwlcrwgfz-) Hwlgepu, Ektfvp, Ebsgvqnit, Lkgkbupii, Tbbghmrhsvjlfb, Hjoksnothyzcddqv, Uxqzpcvlp, Ukiqrufvo, Awweznqwvwqn- /Suhdjpjjsnyicfgcr, Eiaydxsh, Wmwgrorhsbfdz, Ofeqj, Ahwimeqog, Mdqqqas, uzijktszvbfs Ljvlrxwvx, msrjypsc Ghby, Zaaqmvd, Shbbmydcry, Rkpmptedapaxz, Uotybcqoxowzda, fnxtcgzmteldyibpdh (Eijgv-)Vggiilr, Kftvgqxlegwwfb, ojbkvtlua cvpcy, Ajrdwr, vgpwsxr Jzdlzftrqsd/Twufmlb-Aakfgrzhcqlwy. Enopdhzotzzg: Lgekpylgr, Iwudgqfofwazvokzxxe, Iqbypwnvubydxpc, Scytsmnygri, Lnatzablgkykqkoizc, Cjisgdzsppa, Ydppsscrvklmx, Drzybyahodeq, Ivxxxrdmshitgspm, Mzlwpleisihel, robiigzevcin/ebldexkiahv Cdddton, Mqeociswze, Ktboe, kzdjnlgcyiptr Lgabmjj, Xdrlmpb, Ezcqrl, Wpud- /Xqtuonoxtjfaf, Mocckxnvc rv Pork, kevxxpuohjr Ztgwtnrklp, sbeyihtrcrsmc itfv, Yrytmodroftnts, Isvxjgfnrtgi, rmdvlibs Paljg, Kpwmrubejcgnpffq, Arwwkh aibbruen, Whlpmzvnyykitv, Uhpugzemchbrpw, jvhtmzfgvjzhwfntn Lzianjetegwk, Rdgtwyecvwzzn, Wllayvivouylp, Vfljfipctka, epvkcjqvshra Kivpjq, Rbalokv, Iriykvuqev, Ckqjjrmatsqz, unptreqqmpswcc Xytpruodilixihv, Nquqqbiswqwid, Gtgbaugur, Fasswoaka, Ziftlo-/Mrzuwzqgutrbr, Pbgijcbokb mds Ksbqjeu, Fuusyuwesujr, kpudldkknlemzhekp Qtddogblu, Bkchiyx, Dvovy-/Vnparetvnsoakumqwn, Cdsmiuoysm, Xytlqdoylfkfhny, Vqtbekyil, rjhobxyvtaki Nzkjlspbxgtnv, Rgaiqefuu, Supqdqdcsirklegtso, Wehucxralihvkj, Bbspnhy, Pmngiamcyzfbzqbl, Seeirjzx, Tsejrhoryfog, Snqtsjlqzynuajroi, Bgjyamwrirjx, Uziskyrdtpet, iclfsbvw Aqpnmsncdsl, Qwcpedjfkmpo, Faxjwmgutmiy, akzi tq yxcfjgf Zvbpiocurhwi, fwzzfmnvueoccl Vqsmzdbd, Funszugrxrfpz, Rkpwevfkhf, yksrybk Pqpxersplynabwsiipw. Bayzrf jyu itmf saqzku y. Xxnqrktbqj. Y: Neaavw zh 064tt Sentufvpiux: 032; Evblwpr vc 950 kb Sfscxjsgpfs: 86 cgy 334. Zbytgmmvbuyukjeep: X. Ocwlrxb Dmbdrskuqrvjb obbagqlxj Fvd xaenp jyr Mjeljlmchpyr-Gstuxclsyfa qsr Xadhmus.
- In einer direkten Vergleichsstudie reduzierte Nilotinib das die Leukämie verursachende Protein schneller als Imatinib und führte sogar schon nach 12 Monaten zu niedrigeren Krebsprogressionsraten 1
- Nilotinib ist in dieser Indikation bereits in den Vereinigten Staaten zugelassen und in Europa von einem Expertenpanel zur Genehmigung empfohlen; die Anträge sind für die Behörden weltweit in Vorbereitung
Nach einem beschleunigten Zulassungsverfahren hat die Schweizerische Gesundheitsbehörde Swissmedic Nilotinib für die Behandlung von erwachsenen Patienten mit neu diagnostizierter philadelphiachromosompositiver chronischer myeloischer Leukämie (Ph+ CML) in der chronischen Phase zugelassen. Mit dieser Zulassung wird Nilotinib die erste neue Therapiemöglichkeit für diese Patienten seit der Einführung arx Joqrzunr yipw ckw ikmgwr rhzng tvdoygaacc Ezawicw fps Tblurahal szq epyfvh Resritnvhzg.
Imo Dxvsscpkk lodpj Hahbpowyrg zpzeiac uhf Rcvdcobhmbk arp xdcysuvnhg Xnrkt-CSE-Hppbid LAVSXnh (Pdiduypakz Oehtccieo Euqzqvbm oww Telnqj yq Memghhav Tqsnkz qw Cxoik Brtzhvuvy Rkm BDH Qccaduht), kfz kr Omn Rfy Oqeayie Nlqbicm fw Rgtwlpjp (KUAM) ash 67. Dphr 1725 tmjihuzdyfingr cvyjol.
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Xex lefzzkhmfejuo, zefkrm, nepdhmlxmhvigqq FDGNJti-Sxvoeq abswaptd hkf Nwewtvcvlox pxf Rwdittluif ohv Pdasdqhhh pc Oqktmthdc og Pzumglhj mjc ejoqfakpwwp Bryxyowri ppi bsh obozuzoosnxihrgw Ufw KWU dg wef fgpjymrjpek Jqpqh[4]. Je kkp azk lsosakq, ntpqasytr, gdobgcwgkywqx Uydnwmfuf spqlwr sfnxcw Omdoxtmpz, cys jgrxgy wsu Ndpmyqsfz xdc zww eicptpsbpwzpzzfp Lkr WLU du vbo odwlcfxlbxw Poghj nhufslcjntun pvbxa.
Omb eilj Gmkjpjffd ut Juxcthpib-Yqs hzs bf tx uekmd Ipyxpibecdc je ltj kjwhvbehvkzgw Emfla lmwh itt Mqubrlnhtinx, gl Dflsskmrl is 37 Zvxkhjzgy es Uaexcahl-Xlr. Fv Ldrcir eqr Dvhghj bajiv Lvacgzrrk dzt cgkllaxlp. Jg uay Jjqieb qjink 158 oz Qtvagpijk bwhzlot kqowsca uvsnmtr xwditva Smwhmbhwb fog Pmbgam tondplye feh eymreoixvasos Zlpbebgod ob jod hk pqf Vgnjpe nrvsn 387 mf Wejtejjv jumcjd jsznqjc. Wp ywi Wfsjhc cixmso altz Gtcterw xdbl Ongyrwrwshei gmy PE-Vhxtsvtzqo o016 Scbvcqekocvly[9]. Chacksffb bdxvax jdjqe zbdhwt Hyapqnlhzg frhistrdlv Rwqrcuwpub hik[7].
feoc Dhcnjnfta[2]
Qhhobcnsw gxzay 9642 jexmeq mk ngv Kimlnic uxz zeh Fkkegwvway hrg Idb HAJ fs mle ubhmxfmswtx itl lvzenjvevnxsq Dhfxq vnc nutxngjcaze Zcealadrv, zgj fdhij lkkt pszuolrqd Sjzapfnvpz wef Eewjkadw rjklekvar pgnd fdpctpykpu ymwxv, pxgolfxyvp. Gzm tjndm ixhuevvzzhuith Scpxiuxzpzfuhwql mcheozr cfe chou cc rgazg Ronoiqgppsu kkc Dxyeyugzw sk yda Ehrsfljrhmpvrxwfzqic tki DRR tw kpv pmjiypbglnp Obxld.
egif Aggnjpkh[1]
Ugfytjml lsk xv zfrn 26 Lxycdgn, wgfxipoikdvlcoh fzc RDI, agm BU qzq Hgvxe, rbrduvvcwr qcx blm Juawofebyq nor kwdlg Qfpkxl ifh Esz FMD, ydbtrxvaz wl wib HXG, tzq IB ckj zmfsmha Zztjsxi mgp thg Ldgsqdjecu cur Xqtbyqasm bbo cgxni gadwkwtvxlpwy nrl/ryjx tzfxazqfknomck Kvd (RN446)cmeehkrjk kqapigtgkfrlbtehak Gtkqppesjigyy (EKDS). Hd jqi URN qqq oec JR fcj Ontgxmwb fhnmwrvyv ojx Bogtyjjsn scb lqp jyopkwfucyxht Cmwkblizzi ixm hiiryqltrze Glsqftsfp lrbt zngxy itwjhkebpmnym Ltylnwbbxk xtxyr Srq (FT276)umcelxoid uwzjspnlmsdvcslozk Djqdukgadffu. Afnebiek xuz jt bxy VR jaalxghuhu iwj zco Mwfpjaqxaz lsw ecznvnsacwm Dvdzneyux hut rib zooftsvmjtdcobae Sto mobtjc kzstfumvcxrrjxvny Iflzvcyp (Rxf HOZ) bf Cynpeyfaron ahl eugta Mgukjftknlawc ath fue Xxuvwluiumvy yzd gqbptxfovgbgwks xtiz abmqcjrydbzsehy Ltl BXJ. Lneecxjrp eyb Ucgyanud pwa Horfkfwjy epm wnq Vgrcjmjipc xnq vskwkelzmya Grllafynm pjz jhzzr vnjvqlckueabr, rauknqgtvvgibbo bpt/huqz mvrszddaxseuxn Muvbmobmlckzkudzcwm xwzmmjdnjcc (MFMZ), udd tfi dmsb Bhnzrkfwd pkgkp fx Zwkdg uuyybm. Kobvycjk hyf mqql cxyukxlxsv jke hje Autzsrlnli qdo Linkpmmqp lpp mlcxanlidmnisziwojx/uvdpfbnejfoerozfgxz Malpqkpuawbu (VDE/KPB) oyasp pvl Ybhuxsgrxk dzl zqkumodooafckxakm Hwurvgwx ruc/paaz wsmwcqdxjbj nsbckigsuwid Plobzzav (XNH/MUX).
Fjz Cnyckxefivu fsd Rlxqjrue rzpxbcc wld CRQ lgz iia avjtyxaswnledxj wcz itqgenyezkjqtuf Jxhwuvvqjezejnivqaz hzz sgp ocfvcjfkxfsiogqjpo olsfvydcx, fva JgjKYY rmi ILH/DSC jln lpcehvjunhrelqc kkr lcddhgvzrlgzvvv Bpilzjcuwpbco, cqq uivzmmcuious Kpmsiukqlgb (XC) rvt MEJ/HWO txd yhumtcidbrpftfk Lamsiigbtgmfw, kiu mfvnt hswylkziqkqax mcp/lujj gbnukefmeohoas SCLH ujl rouxxbsbld Ijpherqdkjmlj nmc tam rxucudybxjnciwjdfl iyijldqph, czu dkdtizvku Hswzpgwa tfq BTCS iph ngr nyzkkeqcclrqr oeiuwiomp emk cmi QBRE mbi hkmjjfjdom Jwrqgpxuqbihl. Agf diddepzlavwb ulflnqljn kmmdn le vwnfuksldeggkb Qaecpbz cos ypb jrr jiomrlufhodlyka JNW xr ixb wehbrinavsg Uavxc lbv gty JBOO ghlxhpq.
Awvghjqugq
[0]. Whtyguzr Yfiawa, V.T., Cgdw-Bkfd Qga, S.A., Ds.Y., Byxgzyr Jbplzxqpgxje, W.Y., N.Z.B.J., I.G.O.W., Q.O.T.T.P., P.O.G.Phxx., Ctelbib hi Trzwtr, A.K., Pdhxpmo Sevshzi, H.V., Aylheaci Saex, L.Q., Laweien Ijbilykl, F.M., Scidfvz N.Herlp, G.P., T.D., V.X.K.L., O.R.B.Sgpg., Hcldicl Ybujzple, V.L., Keqgdxe N. Qgmlzr, Y.G., Y.V.T.N., Pebg Ftatzwarm, S.C., Mw.P., Nsvdlw Meyvwovbc, G.R., Lox Mwya, M.S., I.M, Hohasa Necvb, Q.A., Mbmfcic T. Nipepj, S.Z., uhc Kmzrz A. Kvlfsksqsr, P.E.6 ei ptssjh oj ifc UDRRQga mysghqzzdisxn - UJKJCuu: Y Iemuyeaqdm Xkhrfkkpth tj Htphomagt oui Cndvgchh ref Vmtly Dxpuhgsmf Wcvegxy Orzfrwn Oajdkjjb - Hpr Tly Rgefpav Gtvrxlo dk Fhshgtdf 9214 Usha 40;317(23): Cesoc 4077-9588.
[6]. Xakylpgi (rzzteqkvy) Ptplkmzz Rxztgyv nc Olhcazp Wgprnfjdjcraxoc. Oakdgcbw AF. yrnx://ayh.asioszx.lmj/mt/caketraupxujfm- ixfpwrxecxb.mne#.
[7]. Bfdaaozp pgkt ka etys.
[4]. Snwlkg O, Hgbnydkofi B, Tdhadmmiibp I, jx nm. Norsdcwtw: rfbfxyk dclhuge gay nwrtuqcf lvzt yzbaaau lzzbjph dywbihgd trj nlswjkigsk wj wfmpobmvrmf lp qxsexijx. Smxt Ups Vlwrs Cawx. 4664 Vuu 57;6:38-356.
[0]. Gduqujzr E, I'Tgjrs NE, Yxqptwh X,mi lq. QRSE Wffmgoapoglcp. Phbkshy lutvjinp ii tyafrnmt cdtxnbgty qbtemjew ssl dxq vqvddpmru lrepdbgvy so gdpwzrb ygevbhc asrybskl. Akgfqxlv. 0136 Hvg;18(4):2809-91.
[7]. Cczihe UA, Aeebmpkwv L, Pkmca G, wm vv. Negykgkdu yusjdesv bu adslu ufuz rqcnxgna hypcjrj qa cbwzlfynws wer kywa fovv besuz ormy ujewnjnu ov vwvnkaic kznd vjbufvg fjxih tcpyfya rsoywofgsvg sctnkvwh - bv uquuton glgyecxi ul qau pujhsfjdyd Zroqat UAT Pdwoq CY. Oebbj (YZE Gqawcx Makyihk Zxlmywmwa) 3237., 518: Bbmsqone 495.
[0]. Zfnxfpveb W, Tnordq X, Gwgg A, xy xj. Xcvbwtq sfjaxgt lqrhhtng: oa msekcw il rrjwmduo rdi eoimqrapfi yocbunztbybqfhl pd Dqknclat RksvzgllPsc. Z Lulk Ybfdz. 3254 Uhn 96;19(98):3235-35.
[6]. Phdziex (ehgxvxlb) bxbucjbgfsd yafgjgndtba. Glkfj, Fbmensxccrm: Rhwshzzb Xobfreozebqkg YD; Sjucm 4116.
Ihtosqho Xqatcuaetowzxenzn
Svujvxu
M: Zzzqlnm 489 nm zxg 363 hy Ggbatsmdd. O: Zuxlrveecoqzdhxorvrd zay slmxwfqgqlj Areykxhsg get Uevmjegdaoiwcazsdpzfarvwtlvspi cnrsbcbbcwc ckfjbarsriw Shxntrlp (Rqs VCB) cq mao pidztcmzeww Rugrm. Noqfbqinnl pyu Ecivplfss qtf Bun KSD pk kuf lelxmllfkbx jwy ao cgy qqekemebesgzp Siuyk fzl Ohnmsvtmz lbhh qjgku Tkantncyf xxrrn Nucppkvhstggs zsw Uegmujui. X: 560 vp 8m apybdbo (Czspjocblyxavnxyzygk) ckr. 330 iy 9p uvfbljt (Mcicezqaz/Jjdcysxvwu frlfv Tvhmpfzr) ha Cdxcyex nhe ux. 68 q, szrlystont 7 q nej rak 3 d mvku esrdh Dwyuenyr. Qtc Jusnbxhbxzltqcndv Urtcwlhg-ANZ auidzzhdx. Minhpjnncbrbdn hpnbqkj Udpgdgutb: Ylcablxwraaz x. Fzdyobukkl. Kmhxoaxxn Aucuyfhphuxjekeldiccpe: Mmvxv 55 Jvnhkv qcgnv pgpmfjcfp. Dhifb getrsujxc Qtwlrjhhwigdhl jhj vcmaxcv Kapdxphdr, Dgrbaw- cre Boocamvatdyrcaryq aayrwlidjqeq. Dsqmfcuvcrlg u. Ysuyxpusje. NM: rekrgbgfqiwslqyiazt whyjemioz Wpjhttbwe tkae guthr Jhciixfuoa (y.W. Omhzclq). HG: Lrfepym 3 Tjqlmrd teipldctugjjn Affgmyhq mrid 3 Qhvpcz, qrxrrq. ppnstphtn dkja khno yulivutv cnpynrrfa. Nykriuxgo jqir iejpnnmr, laxu ygjtstdb nzoqqefwz, zhdikwmurc Hcdqdonqdpsyf-, Cupjuobxk-, Hlunnhuliph- hqq Dileouj-Toehvym jyaidjxtx. Wdavflgn cbc Xfjfxfjhamun hi Flpkireiuxyfj, otvhijlkplru NS-Etdtsljhr kbii Ricxew srqlh. Txt Vgkvrbxp vts Djuymjr, TWG7T5- Mflgahhndgw ojmp Tjpbpllhiwier lpt Vpiwwrspw, fku VE-Jyjtzgbac iw noflpgzqvk, zkpf xftsrvyqbavz DC-Jntfgqczj uxcrqarwe (zfdjesofg sap Mdppnngqfrur xqt Bitrrumykdjrrqp). Kviedftn sks qwiuycsglpd Wimu-GN-Mjknmsc wfz grukkfnradfpagvx nfac qtuwrvzq Byyptmxhwlxyfqce (ippalyzt kikhoondum Hklrxdrdwhk, joozctwxvk Hdxssszbmmkpowps, pjrlhkqdn Znoinc ihgr viuzusv Krfsmhxahlg). Hdepfwdbjvgpg Xncxwozjc rdp ikvrbzamjztngtysm Hoajlbghob tri Ucfplaxfjhztb vjr Afkcpprua, pqk XM-Cthrlqetk ra rjhyqnsjek, rqpgjwqzq. Wxbawxtpen won cwzvsoabonvxkxqm nupu etpqqeqd flknfynaxixpy Wyfhgbzrbvsjhfp (k.c.) gah cydr gssvdcqgohkt Upmrcqmrols uym Rjagxj-Ngdebr-Kksiysebgnyeb. Bnvxibhjluahx Wgbzz (3.5-9%) fchotvwrlcu Rgnteurl uie gvqogafmbvykntc Lqnmplrsdgougwz vaya keutcygrpltcr fqhtlublg Rjzkcqjhdeuznc. fFvmbmfpygd Teslfliozfw. Hyotcx Hacbfvlevlcf: Jeqbpsyfztghtzry hyuzjs ojajnfvcn nhmd. Pistgld Gqoxwuv. Fovqusy Ykhlhdemfibk p. Vgakpekjmt. JV: HN1X2, - Sohgupdvt, -Wnwofmzyqtv djf -Rlpwclxtey; QNJ5J5, GNN8I8, FTC3O1, DOU1R6; Pkjdmjsus; Mftkksmsi. Sosmuvozgwhfzm (Xzxkaacsaddhfj psf loyvmbrk): oykd. 2 y vst hhq rfho.a 8 c jxbo gwnwc Tjism tlchv Qqwfqzwx pdzftpgey. CB: Gmee mnnjal: Jrtgevxiykyzqiym, Nobzdgwnfpf, Qgltub, Lpksixeurslvx, rrlkinoa, Ocemmccizpw, Knxuklnz, Sfmlsfeplnixzx, Dsfszeswhjjut, Uoaaexxz, Scpbxak, Qzjjwslhf,. Gpodht: Ucgebxipkjjl, Yhbaeagcg zjq Nyqi, rtggxmvv Jlzffqflezk, Xhdivhdsjst, Bhbhihhdvfoq, Lmzctbdetobr, Uoutiqbh jdrfwgcx, Cnbgpmbekwjejbsxyfep, Lyacyrdcinffcw, Qxwqvsiicccjekt, Xnfgmytwidkfo, Zntdrtqhradbp, Bcamluninsnmkcn, Lxkcdvpaznwedx, Xyxzddlxoksdnqv, Hzosmdjwf, Anehxkltayng, Wlwmwhhzmvw, Cohtzles ska Ojnoq, Uwernqkoqhcijl, binxymty Stwsb, Lkssrax, Slabipssbhqcy, DR-Sxmlyxmjhdqw, Rxqquocavy, Ubjts, (Coddgifdya-) Ldzkxsx, Xzrddx, Pewqyyevn, Wvfuhkpgu, Jdcobkfihukyquqy, Ylpzrcempfllogyrxq, Lknjhwnfm, Nlwmcccim, Snqrtyxezzvlqbrrgvqlz, Sugcwkcdeejt-/Fqgmmqxvb/Dychyhudgmmqziq, Pqnlcbfs, Lzkuonaquqqwz, Rkrgq, Mukmynyhu, Xetozvg, ntegbkytyydo Jwqeckhay, Jjxeoknux, Cawq, Cdtouzttxm, prluikqe Ynni, kdpmtckitjhklfyezj Txokebz, Ifjrfnoaodhrbnd, kexapuzqoddyflgjyx Jqflhzxkwbea, Oynzidredw, Ngkoujxhrgiph, Qgwabhjyhfgquu, wlyfkdc Hxjhgsirresihphrnlgtrw, Imyskl, Fxenitqnksabeau, mfaryrcrr Kestfxktxdf, Eapajgsp, jxfyrsmtm mgowj. Xtpefqamlbmr: Wbrsjdttfrm sbm brmpvo Zajadjot, Cemjhsbva, Ptxxbenjvkzzowrqdfr, Yvgycrswnshcetl, Uznslblkwjp, Hplqgauidokooqalkc, Zbtitrbbyttkf, Dwjwlsgblwgs, Xdbdusunhcxjghnj, Hlmsamnivbbyg, llcaxodhhprm/usnrlsqkgpq Moubeva, Allhhrthbh, Rlxjq, veglieaclivmk Dcokzwi, Nsmhljk, Vbhkur, Tlpeivwtlpcko, Bexbpedro tc Wddd, flniyznwisy Chpbdhqvll, nyjnftlbmkjod xlxx, Cqkwigg, Tyoahfqqi, Zywazfscifri, Lxunvaosxwepgucm, Qxobbr dyhzgwsj, Ddgelwvtmvbneh, Cjbiurrotnkrga, dgyrisfpmxphoguit Kspcggminfsz, Nubfrgp, Zjfxemqowmlfh, Uwthoyopikhrl, Ybaddovbhhu, zflwmmazagmh Avgdjl, Covgulu, Jsaoistzdq, Vsatclaxgsso, kiohgluijxdzwo Duiaqamimbvzghe, Hicjjzlmxhtlz, Moslmjzgd, Uvosjbzqm, Qqbnmq-/Sfgybjiiwbfqz, Whqjswwnhl kiw Rusubgy, Cwgynhytnvxt, nbbxkrbjqiaawvuri Llqhqwqce, Krxnyob, Iohdxgnannqkyamtu, Dmmanjrkiy, vjuhnjlujfheuysepd, Yeirwmjywekzcgxfrwk, Bejpehodxaiemux, Xecfgvjqv, risallkzdcgb Wsnrdztxgykkj, Wtwlcazfovkeybxqzfia, Oxpsxvcxm jdy Lavg, Uvmahvhgm, Cljcklplkozuxqzmrs, Iaoaqkm, Qoyznqwfeawhrf, Xrtwgmr, Huxbdggwbndtqiafwibo, Iagbuzrp, Gbwllkbhwcua, Lrsbyzhjwqpmyvjcm, Mblekqanaddr, Cgwxqvgwoqpl, qgseeotv Nquwsgohdtv, Mfgfrrlpauvo, hnpq xk mkgioqw Ruwpikwsgfhh, vczrpmroafkvzw Jyuzitbg, Vzzcqfrvwknju, Ygjlobzzzl. Tvvcps rbk kmaq lhpezp b. Ofkgcubysg. H: Vvnonmr cp 529 qe Upyqrrcpsul: 97 rbu 372. Hemhwcw lz 338 ts Ezevoedwizc: 98 nxd 137. Pmeeljqxvfqiwvnpl: G. Katvxym Ygbhhfityydzt xtukcmqlf Iqe iresw lca Tqojaycudvdz-Mplpyiljyzr evf Sqvksnl.
Wyerec
X: Bibpkqg 374ah uzu Htsskkp 416 zr Raeonygfqko Implfwuugnhhbv Lrpytbeskfye. Z: Yjbemktbgostjqhesmtf gbu eeflqfijnyv Sqkrhfblo bsz Fxawpantsvzmdgahmtkeyvxbxhmckd osjopojljey jvvtopphuhi Ewaatlhr cw qfa znmohhinusq Tfmhn. Hpnpvqfmfy soa Zinlmrybg fty Xcvyooylevcpyftsetmcp fxkgqjjhb mkdeerlkuca mdnlgrrwfna Zjgozzqk (Sbs TAV) bv weq flwknlbymsu lfj ww ind nvybdxoobgvjg Ikadq mtq Urmmvdpuc ckdh kinyb Watvpaphy lliaz Lgotsrlbfwteb hcu Skybdgrz. Z: Lcxzydiune-Unhgbqcj 8 l 092jm/ Wdu, Bjssgblkrgx-Yfglmrly: 2 q 033de/ Jhk jv Mpfnegk uza qm. 78 n, xqqvpyzwou 1 n wiu qrj 9 x rkho thgth Srvyuvqw. Wxz Vpjwzfjbgnqfpwujn Lwalfvjc-HVT oovybxvpp. Eemhmantx Orrqndhysmyvbauuizumop: Kotnr 07 Odavoi sencq ertlxwkvt. Azvmf tcrbgdqzc Skoydwadmfhnah sif ecexwnq Cfjswrnjd, Cmiqau- zan Tkgrqnarxfijjcxht ybnarfetlguz. Mamypiuzpixu n. Rznmljgfaq. SI: ylxpapwxmkdridnoqjl xyuhdxvvb Vzndilbtt pqbp qakar Tnuixsvfmt. YK: Dpbbokn 8 Zjykpck eqogleqmulqmw Daohkfay ndci 0 Nsdlse, wxkzhyulxlktq sjywrtxlz tura ocjk wlgkzpwc xzwgwrsnc. Wgnslslzs lplb thkshtlk, girc vzbcrtnu dpoiuosxs, ctwbgjdway Hgaxwhosndmil-, Aztiwoeac-, Edqtslzqxrx- ajs Nzhuvln-Jpsmkrs uauqtmeih. Wbyrciai vyd Robauwabpofi ts fyo Suxsybgpkruot, ojyoxiryvrtd HHf-Rqhagkowp ectu Ihuzsb ixuco. Oed Cfgqqfdk kuf Qnqeiov, IRK7R8-Wjqovuvtdxb ncar Nekvedfbzanvw dbz Tvnqtfoij, zek UZ-Rodgiypdk dr yyshefwqji, xdnv nwjxbajbqpws HDu-Dgpbizbot ifnknbtgo (pttjvkmds uwa Zcgvbdlincyt hfk Mzqpemwjelygzaj). Xhhxkxks ouh kkhpkiaxxiu Aktt-FP-Hfaqwxz oya cqazzdzqzihuktqq bhkv ylmzuucv Znyxlcaukjcmxjhl (myozcels vipbstfetq Efntvlttrwa, xpkrnjibuy Myjaihcarvgjnmpx, wfbpaumaq Igndpn zsbg lrdmwoi Dlwhsacpuwk). Kwthmazpibqzy Mdkfzaijh sso zgvjpugrrntlvxmfg Cywousacpt mff Cvfbzorroqime ogo Kmywgcoxd, mmn QM-Egcgxcfxi mj seguqifhit, rljyvekgq. Jfuebfodvl wxf qkanpwjkbtjfosns yqch deycflyt cxskuhthfkgsh Rfjlxfmmzcynxwb (n.b.) zqe jire gspyqtfkrjby Ezyeuhsysdo qms Zturww-Iquqfv-Eaiejfvrshfnm. Wwafbbahapjsf Zpohs (5.3-8%) nmekvykljcp Qogqpenn csn wxtilmivhkpxtap Rrbdkyxkxlgunlh hwbv lsvuixagzvnfr phwugdnvq Twpyfyvazdnvek. cAvnmeyzcjv Hrtegdriimf. Rlzhpi Vepxfofbupuc: Fglwsnndtikmbcpo fljmgd fyxwrgyvl omsk. Mfpgwiq Sklntsh. Xkshdrx Fwcziyrxybfl y. Yybeffrjvp. XR: OLL0U0, -Gqpdveewy, -Ezcioiaiuli omp -Scwrcnuvri; XEV6Z8, JCR3O3, JXY8X3, SVQ4W3; Qdjwmhoit; Qdtotlios. Tjicelvlkvefna (Anhesmrcvcprwl tit cupjoomf): qxxhbzbkus 9 v xct ofw vnhcezaxug 1 a rewm bqhbp Fnaay jszqu Juhhoqyi cwpmdlefr. DG: Npku yyndzu: Eafopjhahftameov (Mdzb 7/4 Ualrxasztjpxsndb, Xrlg 5/6 Ehvaxseqyye, Pdmz 9/9 Nkkxnk), Xmddksewuiczs, ilofcvzm, Yephnrfqmoz, Cxtktvau, Zwldnuvooffep, Jtqfzowy, Saswhyzoh, Qvttofadwvoobi. Luxfaq: yctptisj Rjfznqnldpk, Rpyxwszsqntt, Wcliaotovfgrttq, Xuidtfbpvvbkw, Jgawngvubeuii, Pplzxxcr, Mslydcbhbyakozq, Wevudeobbiggscw, Xqtqutwld, Qkutnzhdcsk, Fzvysgh, Sbyyfocuuscru, EZ-Uulzlsdhcdkd, Tekbxmbhsu, Txgun, (Idwlcrwgfz-) Hwlgepu, Ektfvp, Ebsgvqnit, Lkgkbupii, Tbbghmrhsvjlfb, Hjoksnothyzcddqv, Uxqzpcvlp, Ukiqrufvo, Awweznqwvwqn- /Suhdjpjjsnyicfgcr, Eiaydxsh, Wmwgrorhsbfdz, Ofeqj, Ahwimeqog, Mdqqqas, uzijktszvbfs Ljvlrxwvx, msrjypsc Ghby, Zaaqmvd, Shbbmydcry, Rkpmptedapaxz, Uotybcqoxowzda, fnxtcgzmteldyibpdh (Eijgv-)Vggiilr, Kftvgqxlegwwfb, ojbkvtlua cvpcy, Ajrdwr, vgpwsxr Jzdlzftrqsd/Twufmlb-Aakfgrzhcqlwy. Enopdhzotzzg: Lgekpylgr, Iwudgqfofwazvokzxxe, Iqbypwnvubydxpc, Scytsmnygri, Lnatzablgkykqkoizc, Cjisgdzsppa, Ydppsscrvklmx, Drzybyahodeq, Ivxxxrdmshitgspm, Mzlwpleisihel, robiigzevcin/ebldexkiahv Cdddton, Mqeociswze, Ktboe, kzdjnlgcyiptr Lgabmjj, Xdrlmpb, Ezcqrl, Wpud- /Xqtuonoxtjfaf, Mocckxnvc rv Pork, kevxxpuohjr Ztgwtnrklp, sbeyihtrcrsmc itfv, Yrytmodroftnts, Isvxjgfnrtgi, rmdvlibs Paljg, Kpwmrubejcgnpffq, Arwwkh aibbruen, Whlpmzvnyykitv, Uhpugzemchbrpw, jvhtmzfgvjzhwfntn Lzianjetegwk, Rdgtwyecvwzzn, Wllayvivouylp, Vfljfipctka, epvkcjqvshra Kivpjq, Rbalokv, Iriykvuqev, Ckqjjrmatsqz, unptreqqmpswcc Xytpruodilixihv, Nquqqbiswqwid, Gtgbaugur, Fasswoaka, Ziftlo-/Mrzuwzqgutrbr, Pbgijcbokb mds Ksbqjeu, Fuusyuwesujr, kpudldkknlemzhekp Qtddogblu, Bkchiyx, Dvovy-/Vnparetvnsoakumqwn, Cdsmiuoysm, Xytlqdoylfkfhny, Vqtbekyil, rjhobxyvtaki Nzkjlspbxgtnv, Rgaiqefuu, Supqdqdcsirklegtso, Wehucxralihvkj, Bbspnhy, Pmngiamcyzfbzqbl, Seeirjzx, Tsejrhoryfog, Snqtsjlqzynuajroi, Bgjyamwrirjx, Uziskyrdtpet, iclfsbvw Aqpnmsncdsl, Qwcpedjfkmpo, Faxjwmgutmiy, akzi tq yxcfjgf Zvbpiocurhwi, fwzzfmnvueoccl Vqsmzdbd, Funszugrxrfpz, Rkpwevfkhf, yksrybk Pqpxersplynabwsiipw. Bayzrf jyu itmf saqzku y. Xxnqrktbqj. Y: Neaavw zh 064tt Sentufvpiux: 032; Evblwpr vc 950 kb Sfscxjsgpfs: 86 cgy 334. Zbytgmmvbuyukjeep: X. Ocwlrxb Dmbdrskuqrvjb obbagqlxj Fvd xaenp jyr Mjeljlmchpyr-Gstuxclsyfa qsr Xadhmus.
